• Publications
  • Influence
On-chip nanohole array based sensing: a review.
  • C. Escobedo
  • Engineering, Medicine
  • Lab on a chip
  • 4 June 2013
The integration of nanohole array based plasmonic sensors into microfluidic systems has enabled the emergence of platforms with unique capabilities and a diversified palette of applications. RecentExpand
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On-chip electroporation and impedance spectroscopy of single-cells
Abstract We present an integrated microplatform for handling, electroporation and label free analysis of single mammalian cells in suspension. Accurate axial positioning of a cell flowing through aExpand
  • 58
  • 4
Radial sample preconcentration.
In this paper we present a radial sample preconcentration strategy enabled by axisymmetric concentration polarization in a microfluidic chamber on a uniform nanoporous film. Sample analytes areExpand
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Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice
Structure of a bacterial adhesin reveals its role in forming a mixed-species symbiotic community with diatoms on sea ice. Bacterial adhesins are modular cell-surface proteins that mediate adherenceExpand
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Microfluidics for sperm analysis and selection
Infertility is a growing global health issue with far-reaching socioeconomic implications. A downward trend in male fertility highlights the acute need for affordable and accessible diagnosis andExpand
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Nanoholes as nanochannels: flow-through plasmonic sensing.
We combine nanofluidics and nanoplasmonics for surface-plasmon resonance (SPR) sensing using flow-through nanohole arrays. The role of surface plasmons on resonant transmission motivates theExpand
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Optofluidic concentration: plasmonic nanostructure as concentrator and sensor.
The integration of fluidics and optics, as in flow-through nanohole arrays, has enabled increased transport of analytes to sensing surfaces. Limits of detection, however, are fundamentally limited byExpand
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Polycaprolactone- and polycaprolactone/ceramic-based 3D-bioplotted porous scaffolds for bone regeneration: A comparative study.
One of the critical challenges that scaffolding faces in the organ and tissue regeneration field lies in mimicking the structure, and the chemical and biological properties of natural tissue. AExpand
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Mitotic cells contract actomyosin cortex and generate pressure to round against or escape epithelial confinement
Little is known about how mitotic cells round against epithelial confinement. Here, we engineer micropillar arrays that subject cells to lateral mechanical confinement similar to that experienced inExpand
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Quantification of ovarian cancer markers with integrated microfluidic concentration gradient and imaging nanohole surface plasmon resonance.
Nanohole array-based biosensors integrated with a microfluidic concentration gradient generator were used for imaging detection and quantification of ovarian cancer markers. Calibration curves basedExpand
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