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Individual differences in the phase and amplitude of the human circadian temperature rhythm: with an emphasis on morningness–eveningness
TLDR
An association between circadian rhythm temperature phase and amplitude was found, in that subjects with more delayed phases had larger amplitudes and the greater amplitude was due to lower nocturnal temperature.
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Combinations of Bright Light, Scheduled Dark, Sunglasses, and Melatonin to Facilitate Circadian Entrainment to Night Shift Work
TLDR
Combination of intermittent bright light during the night shift, sunglasses (as dark as possible) during the commute home, and a regular, early daytime dark/sleep period if the goal is complete circadian adaptation to night-shift work is recommended.
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Bright light treatment of winter depression: a placebo-controlled trial.
TLDR
Bright light therapy had a specific antidepressant effect beyond its placebo effect, but it took at least 3 weeks for a significant effect to develop, and it took more of the complete or almost complete remissions than placebo.
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Advancing human circadian rhythms with afternoon melatonin and morning intermittent bright light.
TLDR
Afternoon melatonin, morning intermittent bright light, and a gradually advancing sleep schedule advanced circadian rhythms almost 1 h/d and thus produced very little circadian misalignment.
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The effects of prior light history on the suppression of melatonin by light in humans
TLDR
It is suggested that the circadian system's sensitivity to light can be affected by a recent change in light history, as assessed by the magnitude of the suppression of melatonin secretion by nocturnal light.
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The dim light melatonin onset following fixed and free sleep schedules
TLDR
The results indicate that the DLMO can be readily estimated in people whose sleep times are minimally affected by work, class and family commitments, and if this method will apply to the elderly and patients with circadian rhythm disorders.
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Human phase response curves to three days of daily melatonin: 0.5 mg versus 3.0 mg.
TLDR
The aim was to generate a PRC to 0.5 mg of oral melatonin and compare it to the authors' previously published 3.0 mg PRC generated using the same protocol, and found the optimal administration time for advances and delays is later for the lower dose of melatonin.
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SLEEP LOGS OF YOUNG ADULTS WITH SELF-SELECTED SLEEP TIMES PREDICT THE DIM LIGHT MELATONIN ONSET
TLDR
It is concluded that the circadian phase of normal, healthy day-active young adults can be accurately predicted using sleep times recorded on sleep logs (and verified by actigraphy), even when the sleep schedules are irregular.
View on Taylor & Francis
A three pulse phase response curve to three milligrams of melatonin in humans
TLDR
A three pulse phase response curve (PRC) to exogenous melatonin (3 mg) is generated by administering it to free‐running subjects and demonstrates that using exogenousmelatonin as a sleep aid at night has minimal phase shifting effects.
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Intermittent bright light and exercise to entrain human circadian rhythms to night work.
TLDR
Intermittent bright- light groups had significantly larger phase delays than dim-light groups, and 94% of subjects who received bright light had phase shifts large enough for the temperature minimum to reach daytime sleep.
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