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Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis
Recent data associate eosinophilic esophagitis (EoE) with IgG4 rather than IgE, but its significance and function have not been determined. Our aims were to measure esophageal IgG4 levels and to… Expand
Pediatric Hypereosinophilia: Characteristics, Clinical Manifestations, and Diagnoses.
- D. Burris, C. E. Rosenberg, +4 authors P. Fulkerson
- The journal of allergy and clinical immunology…
- 1 November 2019
BACKGROUND Eosinophilia is associated with various conditions, including allergic, infectious, and neoplastic disorders. The diagnostic differential is broad, and data on hypereosinophilia in… Expand
Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia.
- Lauren A DiTommaso, C. E. Rosenberg, +6 authors M. Rothenberg
- The Journal of allergy and clinical immunology
- 1 May 2019
Pediatric eosinophilic colitis (EC) is a rare disease with a prevalence of ∼1/63,000 individuals, and at our tertiary care pediatric medical center, only 2% of patients with the ICD-9/10 code for EC… Expand
Prenatal and perinatal history in Kabuki Syndrome
- C. E. Rosenberg, Tara Daly, C. Hung, Irene Hsueh, Andrew W. Lindsley, O. Bodamer
- American journal of medical genetics. Part A
- 1 January 2020
Kabuki syndrome (KS) is a disorder of epigenetic dysregulation due to heterozygous mutations in KMT2D or KDM6A, genes encoding a lysine‐specific methyltransferase or demethylase, respectively. The… Expand
Esophageal IgG4 Levels Are Elevated in Pediatric Eosinophilic Esophagitis and Correlate with Esophageal Histopathology Including Levels of Eosinophils
How I Do It: Approach to Eosinophilia Presenting with Pulmonary Symptoms.
Eosinophilia with pulmonary involvement is characterized by the presence of peripheral blood eosinophilia, typically ≥500 cells/mm3; pulmonary symptoms and physical exam findings, which are… Expand