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In vivo evaluation of the stratum corneum barrier function in blacks, Caucasians and Asians with two noninvasive methods.
TLDR
It was showed that, with both noninvasive methods, removal of the stratum corneum increased permeability, with racial differences, as well as the lag time before the vasodilation induced by application of methyl nicotinate. Expand
Prophylactic Tranexamic Acid and ϵ-Aminocaproic Acid for Primary Myocardial Revascularization
TLDR
It is concluded that either high-dose tranexamic acid or ϵ-aminocaproic acid effectively reduces transfusions in patients undergoing primary, elective myocardial revascularization. Expand
In vivo evaluation in man by two noninvasive methods of the stratum corneum barrier function after physical and chemical modifications
TLDR
Two noninvasive methods are investigated: transepidermal water loss (TEWL) determination measured with an evaporimeter, and Laser Doppler velocimetry (LDV) to measure the lag time before the vasodilatation induced by application of methyl and hexyl nicotinates. Expand
Prophylactic tranexamic acid and epsilon-aminocaproic acid for primary myocardial revascularization.
TLDR
It is concluded that either high-dose tranexamic acid or epsilon-aminocaproic acid effectively reduces transfusions in patients undergoing primary, elective myocardial revascularization. Expand
Effects of five alpha-blockers on the hypogastric nerve stimulation of the canine lower urinary tract.
TLDR
Intravenous injections of prazosin, phentolamine, thymoxamine, phenoxybenzamine and yohimbine inhibited the urethral pressure increase in a dose-dependent manner, but the increase in bladder pressure was not modified by these alpha-blockers. Expand
A two-center study evaluating the hemodynamic and pharmacodynamic effects of cisatracurium and vecuronium in patients undergoing coronary artery bypass surgery.
TLDR
There is no evidence of a hemodynamic difference between the two neuromuscular blocking drugs (NMBDs) and there are some clinical and cost advantages in favor of cisatracurium. Expand
Assessment of the arterial tonometer (N-CAT) for the continuous blood pressure measurement in rapid atrial fibrillation
TLDR
The accuracy and reliability of TBP relative to directly measured invasive blood pressure (IBP) in ten haemodynamically stable postoperative cardiac patients who were in rapid atrial fibrillation (HR ≥ 100 bpm) was evaluated. Expand
[Measurement of cutaneous blood flow by laser Doppler velocimetry. Importance of probe effect and solvent effect after topical application].
TLDR
Data suggest that in any protocol for L.D.V. determination an absolute control and a vehicle control should be included to evaluate objectively topical vasoactive drugs. Expand
Pharmacokinetics of a prodrug thymoxamine: Dose-dependence of the metabolite ratio in healthy subjects
SummaryThymoxamine, a prodrug, is rapidly deacetylated in the plasma to give two phase I metabolites, DMAT and DAT, which are further sulpho and glucuro-conjugated and then excreted mainly in theExpand
1ISG-029 Impact of the implementation of the enfit system on the administration of enteral medication
TLDR
The in-vitro study has shown that the change of connectors prevents the direct introduction of micro-granules at the site of administration in the ENFit system, which complicates the enteral administration of drugs in the form of micro,granules. Expand
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