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Visualizing an Olfactory Sensory Map
TLDR
A genetic approach is developed to visualize axons from olfactory sensory neurons expressing a given odorant receptor, as they project to the Olfactory bulb, which provides direct support for a model in which a topographic map of receptor activation encodes odor quality in the ofactory bulb. Expand
A novel family of genes encoding putative pheromone receptors in mammals
TLDR
Sequence analysis indicates that a family of about 30 putative receptor genes comprise a novel family of seven transmembrane domain proteins unrelated to the receptors expressed in the MOE, likely to encode mammalian pheromone receptors. Expand
A Novel Family of Putative Pheromone Receptors in Mammals with a Topographically Organized and Sexually Dimorphic Distribution
TLDR
Patterns of receptor gene expression suggest that the VNO is organized into discrete and sexually dimorphic functional units that may permit segregation of pheromone signals leading to specific arrays of behaviors and neuroendocrine responses. Expand
Molecular detection of pheromone signals in mammals: from genes to behaviour
The instinctive and species-specific behavioural response of animals to pheromones has intrigued biologists for a long time. Recent molecular and electrophysiological approaches have provided newExpand
Loss of Sex Discrimination and Male-Male Aggression in Mice Deficient for TRP2
TLDR
This study suggests that, in the mouse, sensory activation of the VNO is essential for sex discrimination of conspecifics and thus ensures gender-specific behavior. Expand
Loss of sex discrimination and male-male aggression in mice deficient for TRP2.
TLDR
This study suggests that, in the mouse, sensory activation of the VNO is essential for sex discrimination of conspecifics and thus ensures gender-specific behavior. Expand
Superresolution Imaging of Chemical Synapses in the Brain
TLDR
A superresolution fluorescence imaging method is presented to visualize the molecular architecture of synapses in the brain using multicolor, three-dimensional stochastic optical reconstruction microscopy, which allows molecular events associated with synaptic plasticity to be resolved at the single-synapse level. Expand
A Map of Pheromone Receptor Activation in the Mammalian Brain
TLDR
Observations indicate that the organization of the vomeronasal sensory afferents is dramatically different from that of the main olfactory system, and these differences have important implications for the logic of Olfactory coding in the vomeenasal organ. Expand
High-Resolution Analysis of Parent-of-Origin Allelic Expression in the Mouse Brain
TLDR
A genome-wide characterization of imprinting in the mouse embryonic and adult brain uncovered parent-of-origin allelic effects of more than 1300 loci and identified parental bias in the expression of individual genes and of specific transcript isoforms, with differences between brain regions. Expand
Molecular Organization of Vomeronasal Chemoreception
TLDR
It is demonstrated that the two classes (V1R and V2R) of vomeronasal receptors use fundamentally different strategies to encode chemosensory information, and that distinct receptor subfamilies have evolved towards the specific recognition of certain animal groups or chemical structures. Expand
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