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Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy.

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A Consensus Molecular Classification of Muscle-invasive Bladder Cancer

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Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer

TLDR
A missense variant (rs2294008) in the PSCA gene showed consistent association with bladder cancer in US and European populations and was identified as a new bladder cancer susceptibility locus.
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Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice.

TLDR
Therapy with anti-EGFR MAb C225 has a significant antitumor effect mediated, in part, by inhibition of angiogenesis, and down-regulation of these angiogenic factors preceded the involution of blood vessels.
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Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer.

TLDR
Overall, this is the first epidemiologic study showing that miRNA-related genetic variants may affect bladder cancer risk individually and jointly.
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Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer

TLDR
The results suggest that EMT coordinately regulates drug resistance and muscle invasion/metastasis in urothelial cancer and is a dominant feature of overall cancer biology.
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Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use

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Stage specific guidelines for surveillance after radical nephrectomy for local renal cell carcinoma.

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Surgical management of renal cell carcinoma with inferior vena cava tumor thrombus.

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Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer

Whole-genome analyses have revealed that muscle-invasive bladder cancers (MIBCs) are heterogeneous and can be grouped into basal and luminal subtypes that are highly reminiscent of those found in…
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