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Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy.
A Consensus Molecular Classification of Muscle-invasive Bladder Cancer
Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer
A missense variant (rs2294008) in the PSCA gene showed consistent association with bladder cancer in US and European populations and was identified as a new bladder cancer susceptibility locus.
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice.
- P. Perrotte, T. Matsumoto, C. Dinney
- BiologyClinical cancer research : an official journal of…
- 1 February 1999
Therapy with anti-EGFR MAb C225 has a significant antitumor effect mediated, in part, by inhibition of angiogenesis, and down-regulation of these angiogenic factors preceded the involution of blood vessels.
Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer.
Overall, this is the first epidemiologic study showing that miRNA-related genetic variants may affect bladder cancer risk individually and jointly.
Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer
The results suggest that EMT coordinately regulates drug resistance and muscle invasion/metastasis in urothelial cancer and is a dominant feature of overall cancer biology.
Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use
Stage specific guidelines for surveillance after radical nephrectomy for local renal cell carcinoma.
Surgical management of renal cell carcinoma with inferior vena cava tumor thrombus.
Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer
Whole-genome analyses have revealed that muscle-invasive bladder cancers (MIBCs) are heterogeneous and can be grouped into basal and luminal subtypes that are highly reminiscent of those found in…