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A cafeteria diet modifies the response to chronic variable stress in rats
Stress is known to lead to metabolic and behavioral changes. To study the possible relationships between stress and dietary intake, male Sprague-Dawley rats were fed one of three diets for 6 weeks:Expand
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Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon
Context: Althaea officinalis Linn. (Malvaideae) flower is commonly used in folk medicine in Lebanon and neighboring countries. Although most of the studies have been conducted on the mucilage-richExpand
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Effect of Urtica dioica extract intake upon blood lipid profile in the rats.
Aqueous (150 mg/kg/day) and to a lesser extent petroleum ether (20 mg/kg/day) extract of Urtica dioica given for 30 days to rats fed with normal or high-fat diet, improved the blood lipid profile.Expand
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Hepatoprotective, Antioxidant, and Anticancer Effects of the Tragopogon porrifolius Methanolic Extract
Tragopogon porrifolius (Asteraceae), commonly referred to as white salsify, is an edible herb used in Lebanese folk medicine to treat cancer and liver dysfunction. In this study, we investigated theExpand
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
BackgroundDaucus carota L.ssp.carota (wild carrot), an herb used in folk medicine worldwide, was recently demonstrated to exhibit anticancer activity. In this study we examined the anticancer effectExpand
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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells.
BACKGROUND In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheralExpand
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Leishmania major: interleukin-13 increases the infection-induced hyperalgesia and the levels of interleukin-1beta and interleukin-12 in rats.
Interleukin-13 (IL-13) is a powerful anti-inflammatory cytokine that was previously shown to be a susceptibility factor for Leishmania major (L. major) infection. In this study we report a differentExpand
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Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet
BackgroundSalvia libanotica (S. Libanotica) is a commonly used herb in folk medicine in Lebanon and the Middle East. The present study aimed to assess the scientific basis for the therapeutic use ofExpand
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Synthesis, biological evaluation and modeling of hybrids from tetrahydro-1H-pyrazolo[3,4-b]quinolines as dual cholinestrase and COX-2 inhibitors.
New tetrahydro-1H-pyrazolo[3,4-b]quinoline derivatives were designed, synthesized and characterized as dual anticholinestrase and cyclooxygenase-2 inhibitors. The in vitro and in vivoExpand
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways.
Previous studies in our laboratory showed that Daucus carota oil extract (DCOE) possesses in vitro and in vivo anticancer activities. Chemical analysis of DCOE led to the isolation ofExpand
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