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Peptidomic comparison and characterization of the major components of the venom of the giant ant Dinoponera quadriceps collected in four different areas of Brazil.
UNLABELLED Despite the noxious effects inflicted by Dinoponera ant's envenomation, the information about the biological properties and composition of their venom is still very limited. Ants from theExpand
BcsTx3 is a founder of a novel sea anemone toxin family of potassium channel blocker
Sea anemone venoms have become a rich source of peptide toxins which are invaluable tools for studying the structure and functions of ion channels. In this work, BcsTx3, a toxin found in the venom ofExpand
Tityus serrulatus scorpion venom and toxins: an overview.
Tityus serrulatus is considered the most dangerous scorpion in South America and responsible for most of the fatal cases. This review will focus on Tityus serrulatus scorpion venom (Tsv), itsExpand
Minor snake venom proteins: Structure, function and potential applications.
Snake venoms present a great diversity of pharmacologically active compounds that may be applied as research and biotechnological tools, as well as in drug development and diagnostic tests forExpand
From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery
Animal poisons and venoms are comprised of different classes of molecules displaying wide-ranging pharmacological activities. This review aims to provide an in-depth view of toxin-based compoundsExpand
Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom
Scorpion toxins targeting voltage‐gated sodium (NaV) channels are peptides that comprise 60–76 amino acid residues cross‐linked by four disulfide bridges. These toxins can be divided in two groups (αExpand
Isolation and functional characterization of proinflammatory acidic phospholipase A2 from Bothrops leucurus snake venom.
In the present study, an acidic PLA(2), designated Bl-PLA(2), was isolated from Bothrops leucurus snake venom through two chromatographic steps: ion-exchange on CM-Sepharose and hydrophobicExpand
Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus.
Voltage-gated potassium channel toxins (KTxs) are basic short chain peptides comprising 23-43 amino acid residues that can be cross-linked by 3 or 4 disulfide bridges. KTxs are classified into fourExpand
Serrumab: A human monoclonal antibody that counters the biochemical and immunological effects of Tityus serrulatus venom
In Brazil, the species Tityus serrulatus is responsible for the most severe cases of scorpion envenomation. There is currently a need for new scorpion anti-venoms that are more effective and lessExpand
The proteomic profile of Stichodactyla duerdeni secretion reveals the presence of a novel O-linked glycopeptide.
UNLABELLED Sea anemones represent one of the emerging groups of interest concerning venomous animals in toxinology and the goal of the present work was the prospection, and the structural andExpand