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Lung epithelial fluid transport and the resolution of pulmonary edema.

There is convincing evidence that active sodium and chloride transporters are expressed in the distal lung epithelium and are responsible for the ability of the lung to remove alveolar fluid at the time of birth as well as in the mature lung when pathological conditions lead to the development of pulmonary edema.
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Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha.

Data indicate that, during prolonged hypoxia, HIF-alpha proteins negatively regulate Hif-1alpha expression through an increase in aHIF and destabilization of HIF -1alpha mRNA, likely conveys target gene specificity.
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Nutritional Consequences of Adjustable Gastric Banding and Gastric Bypass: A 1-year Prospective Study

Severe nutritional deficits can be avoided after bariatric surgery if patients are systematically supplemented with multivitamin and carefully monitored, however, specific care is required to avoid iron and vitamin B12 deficiencies, anemia, and protein malnutrition.
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Hypoxia downregulates expression and activity of epithelial sodium channels in rat alveolar epithelial cells.

It is concluded that hypoxia induced a downregulation of expression and activity of epithelial Na channels and Na,K-ATPase in alveolar cells and this was associated with complete functional recovery.
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Prolonged Hypoxia Differentially Regulates Hypoxia-inducible Factor (HIF)-1α and HIF-2α Expression in Lung Epithelial Cells

Data indicate that, during prolonged hypoxia, HIF-α proteins negatively regulate Hif-1α expression through an increase in aHIF and destabilization of HIF/2α mRNA, which likely conveys target gene specificity.
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Comparison of Nutritional Consequences of Conventional Therapy of Obesity, Adjustable Gastric Banding, and Gastric Bypass

RYGBP is more efficient than AGB in correcting obesity, but this operation is associated with a higher frequency of nutritional deficits that should be carefully monitored.
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The Impact of Bariatric Surgery on Comorbidities and Medication Use Among Obese Patients

Bariatric surgery was associated with significant reductions in reported claims for short- and long-term health outcomes and reduced medication use for major disease categories.
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Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo.

Findings suggest that release of VEGF synthesized by AEC may target not only endothelial cells but also other alveolar cells, including macrophages and epithelial cells, as well as bronchoalveolar lavage fluid.
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Inhibition of Na-K-ATPase activity after prolonged hypoxia in an alveolar epithelial cell line.

It is indicated that prolonged hypoxic exposure impairs Na-K-ATPase activity in SV40 ATII cells and may therefore decrease the vectorial sodium transport by alveolar epithelium.
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Cardiovascular remodelling and extracellular fluid excess in early stages of chronic kidney disease.

This study shows that CV remodelling and ECF excess occurred at a very early stage of CKD, indicating that early therapeutic control of ECF may reduce CV events in CKD patients.
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