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Limited effect of recombinant porcine interleukin-12 on porcine lymphocytes due to a low level of IL-12 beta2 receptor.
TLDR
Rec recombinant porcine IL-12 was expressed in a swine poxvirus system as a biologically active heterodimer and used to stimulate bovine or swine lymphoblast cells to support a mechanism for IL- 12 stimulation in swine inconsistent with that observed in conventional models. Expand
Recombinant pseudorabies virus carrying a plasmodium gene: herpesvirus as a new live viral vector for inducing T- and B-cell immunity.
TLDR
It is concluded that recombinant pseudorabies virus (PRV) worked successfully as a live vaccine vector to induce both antibodies and CTL, albeit non-protective in vivo, and the herpesviruses should be considered as subunit vaccines where T- and B-cell immunity is required. Expand
Evaluation of vaccines designed to induce protective cellular immunity against the Plasmodium yoelii circumsporozoite protein: vaccinia, pseudorabies, and Salmonella transformed with circumsporozoite
TLDR
No protection or delay in prepatent period was seen in any of the experimental animals when challenged with 200 (vaccinia, pseudorabies) or 100 (salmonella) sporozoites, although mice immunized with irradiation-attenuated sporozoite challenge were consistently protected against challenge with greater than 10(4) sporzoites. Expand
Immunogenicity and protective efficacy of ApxIA and ApxIIA DNA vaccine against Actinobacillus pleuropneumoniae lethal challenge in murine model.
TLDR
Results show that the divalent DNA vaccine could confer the best protection and indicates that DNA immunization should facilitate the development of a 'third-generation' of vaccines and provide a novel strategy against A. pleuropneumoniae infection. Expand
Erratum to “Limited effect of recombinant porcine Interleukin-12 on porcine lymphocytes due to a low level of IL-12 Beta2 receptor” [Vet. Immunol. Immunopathol. 89 (2002) 133–148]
Erratum to ‘‘Limited effect of recombinant porcine Interleukin-12 on porcine lymphocytes due to a low level of IL-12 Beta2 receptor’’ [Vet. Immunol. Immunopathol. 89 (2002) 133–148] G.I.Expand
The development of DNA vaccine and adjuvant against Actinobacillus pleuropneumoniae
TLDR
The results showed that the bivalent DNA vaccine provided better protective efficacy than monovalent vaccine or inactivated vaccine and suggests that these DNA vaccines and adjuvants are promising candidates and could facilitate the development of a novel strategy against APP infection. Expand