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Estimating Community Drug Abuse by Wastewater Analysis
TLDR
Searching the sewage for excreted compounds relevant to public health issues appears to have the potential to become a convenient source of real-time epidemiologic information. Expand
Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry.
TLDR
This method for the determination of cocaine, amphetamines, morphine, cannabinoids, methadone, and some of their metabolites in wastewater could be useful to estimate and monitor drug consumption in the population in real time, helping social scientists and authorities to combat drug abuse. Expand
Cocaine in surface waters: a new evidence-based tool to monitor community drug abuse
TLDR
It is shown for the first time that an illicit drug, cocaine, is present in the aquatic environment, namely untreated urban waste water and a major river, and used environmental cocaine levels for estimating collective consumption of the drug. Expand
Illicit drugs, a novel group of environmental contaminants.
TLDR
The data indicate that residues of drugs of abuse have become widespread surface water contaminants in populated areas, and since most of these residues still have potent pharmacological activities, their presence in the aquatic environment may have potential implications for human health and wildlife. Expand
Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility
TLDR
It is demonstrated that migration-stimulating factor (MSF), a poorly studied oncofoetal isoform of fibronectin, is a new molecule associated with the M2 polarization of Mϕ and expressed by TAMs, which may contribute to M ϕ-mediated promotion of cancer cell invasion and metastasis. Expand
Pharmaceuticals in the Environment in Italy: Causes, Occurrence, Effects and Control
TLDR
This work reviews the papers dealing with environmental contamination by pharmaceuticals in Italy with the aim of providing a comprehensive view on a national scale, and suggests that pharmaceuticals are widespread contaminants, entering the environment from a myriad of scattered points. Expand
Mass spectrometric analysis of illicit drugs in wastewater and surface water.
TLDR
An overview of the most widely used illicit drugs and of the analytical methods used for their detection in wastewater and surface water is presented here. Expand
Prostaglandin and thromboxane synthesis by human intracranial tumors.
TLDR
Prostaglandin (PG) and thromboxane production by homogenates of human intracranial tumors and "normal" brain from tumor-bearing patients was studied and prostanoid profiles were different for gliomas and meningiomas, but similar for gluomas and their nontumoral counterpart. Expand
Neuroprotective Effects of Toll-Like Receptor 4 Antagonism in Spinal Cord Cultures and in a Mouse Model of Motor Neuron Degeneration
TLDR
New understanding is added of the role of TLR4 in mediating neurotoxicity in the spinal cord andTLR4 antagonists could be considered in future studies as candidate protective agents for motor neurons in degenerative diseases. Expand
Proteome analysis for the identification of in vivo estrogen‐regulated proteins in bone
TLDR
The data suggest that some proteins related to cytoskeleton and to energy pathways, such as tropomyosins, aconitase 2 and enolase beta, might be new molecular targets responsive to the effects of estrogen. Expand
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