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Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
Bladder cancer is one of the most common cancers worldwide, with transitional cell carcinoma (TCC) being the predominant form. Here we report a genomic analysis of TCC by both whole-genome and… Expand
Variable morphology of the suprascapular notch: An investigation and quantitative measurements in Chinese population
Although several morphological variations and classification of the suprascapular notch (SSN) were reported in western populations, little attention has been paid to this anatomic issue in the… Expand
Circulating asprosin concentrations are increased in type 2 diabetes mellitus and independently associated with fasting glucose and triglyceride.
- L. Zhang, C. Chen, N. Zhou, Yuming Fu, Xingbo Cheng
- Medicine, Chemistry
- Clinica chimica acta; international journal of…
- 1 November 2017
BACKGROUND Asprosin has been identified as a novel hormone enriched in white adipose tissue and is pathologically increased in insulin-resistant mice and humans. However, information regarding the… Expand
Predicting protein structural class based on multi-features fusion.
- C. Chen, Lixuan Chen, X. Zou, Pei-xiang Cai
- Biology, Medicine
- Journal of theoretical biology
- 21 July 2008
Structural class characterizes the overall folding type of a protein or its domain and the prediction of protein structural class has become both an important and a challenging topic in protein… Expand
Functional characterization of five CYP2C8 variants and prediction of CYP2C8 genotype-dependent effects on in vitro and in vivo drug–drug interactions
- Yiwen Gao, D. Liu, H. Wang, J. Zhu, C. Chen
- Medicine, Chemistry
- Xenobiotica; the fate of foreign compounds in…
- 11 June 2010
To analyze the polymorphic activities of CYP2C8 and evaluate their impact on drug inhibitory potential, three CYP2C8 allelic variants (CYP2C8.2, CYP2C8.3, and CYP2C8.4), two non-synonymous single… Expand
Prediction of protein secondary structure content by using the concept of Chou's pseudo amino acid composition and support vector machine.
Protein secondary structure carries information about local structural arrangements. Significant majority of successful methods for predicting the secondary structure is based on multiple sequence… Expand
Epithelial-to-mesenchymal transition and cancer stem(-like) cells in head and neck squamous cell carcinoma.
- C. Chen, M. Zimmermann, I. Tinhofer, A. Kaufmann, A. Albers
- Medicine, Biology
- Cancer letters
- 10 September 2013
Head and neck squamous cell carcinoma (HNSCC) is the 6th commonest cancer worldwide. Relapse, thought to involve cancer stem(-like) cells (CSCs), and the development of metastases are common and… Expand
Brainstem Auditory Function at Term in Preterm Babies With and Without Perinatal Complications
Functional integrity of the auditory brainstem was studied at term in babies born at 30–36 wk of gestation using maximum length sequence brainstem auditory evoked response (MLS BAER). Compared with… Expand
A Glycine soja 14-3-3 protein GsGF14o participates in stomatal and root hair development and drought tolerance in Arabidopsis thaliana.
It is well established that 14-3-3 proteins are key regulators of multiple stress signal transduction cascades. However, the biological functions of soybean 14-3-3 proteins, especially in plant… Expand
Inheritance of photoperiodic induction of larval diapause in the Asian corn borer Ostrinia furnacalis
The Asian corn borer Ostrinia furnacalis (Guenenters facultative diapause as fully-developed larvae in response to short-day conditions. As a consequence of geographical variation in photoperiodic… Expand