• Publications
  • Influence
Guidelines for the use and interpretation of assays for monitoring autophagy
TLDR
These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. Expand
Silver nanoparticles: partial oxidation and antibacterial activities
  • C. Lok, C. Ho, +6 authors C. Che
  • Chemistry, Medicine
  • JBIC Journal of Biological Inorganic Chemistry
  • 16 February 2007
TLDR
The results show that the antibacterial activities of silver nanoparticles are dependent on chemisorbed Ag+, which is readily formed owing to extreme sensitivity to oxygen. Expand
Proteomic analysis of the mode of antibacterial action of silver nanoparticles.
  • C. Lok, C. Ho, +6 authors C. Che
  • Chemistry, Medicine
  • Journal of proteome research
  • 16 March 2006
TLDR
Silver nanoparticles (nano-Ag) are potent and broad-spectrum antimicrobial agents and appear to be an efficient physicochemical system conferring antimicrobial silver activities. Expand
Topical Delivery of Silver Nanoparticles Promotes Wound Healing
  • Jun Tian, Kenneth K. Y. Wong, +5 authors P. Tam
  • Medicine
  • ChemMedChem
  • 15 January 2007
TLDR
It is found that rapid healing and improved cosmetic appearance occur in a dose‐dependent manner and silver nanoparticles exert positive effects through their antimicrobial properties, reduction in wound inflammation, and modulation of fibrogenic cytokines. Expand
Silver Nanoparticles Inhibit Hepatitis B virus Replication
TLDR
Silver nanoparticles could inhibit the in vitro production of HBV RNA and extracellular virions and hypothesize that the direct interaction between these nanoparticles and HBV double-stranded DNA or viral particles is responsible for their antiviral mechanism. Expand
Silver nanoparticles fabricated in Hepes buffer exhibit cytoprotective activities toward HIV-1 infected cells.
Silver nanoparticles fabricated in Hepes buffer exhibit potent cytoprotective and post-infected anti-HIV-1 activities toward Hut/CCR5 cells.
Further Evidence of the Anti‐inflammatory Effects of Silver Nanoparticles
TLDR
It is shown that silver nanoparticles (nAg) may also have significant anti‐inflammatory effects in a postoperative peritoneal adhesion model, providing further insight into the biological actions of nAg as well as a potentially novel therapy for peritoneAL adhesions in clinical surgery. Expand
Oxidative dissolution of silver nanoparticles by biologically relevant oxidants: a kinetic and mechanistic study.
TLDR
It is demonstrated that the toxicities of AgNPs in both bacteria and mammalian cells are enhanced in the presence of H(2)O(2), thereby highlighting the biological relevance of investigating the oxidative dissolution ofAgNPs. Expand
Platinum(II) complexes with dipyridophenazine ligands as human telomerase inhibitors and luminescent probes for G-quadruplex DNA.
TLDR
Using a biotinylated-primer extension telomerase assay, 1 was shown to be an effective inhibitor of human telomersase in vitro, with a telIC50 value of 760 nM. Expand
Gold nanoparticles and imaging mass spectrometry: double imaging of latent fingerprints.
TLDR
Certain distinctive properties of gold nanoparticles (AuNPs) are integrated with imaging mass spectrometry for both the visualization and molecular imaging of LFPs to provide evidence on individual identity and resolve overlapping fingerprints and detect hazardous substances. Expand
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