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Rapid Initiation of Apoptosis by Photodynamic Therapy
Abstract— Photodynamic therapy (PDT) of neoplastic cell lines is sometimes associated with the rapid initiation of apoptosis, a mode of cell death that results in a distinct pattern of cellular andExpand
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The Role of Subcellular Localization in Initiation of Apoptosis by Photodynamic Therapy
Rapid initiation of apoptosis can be induced by photodynamic therapy, depending on the cell line and sensitizer employed. In this study, we evaluated the photodynamic responses to two structurallyExpand
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Heterodimers of nanoparticles: formation at a liquid-liquid interface and particle-specific surface modification by functional molecules.
On the basis of a fundamental property of nanoparticles, the self-assembling at a liquid-liquid interface to form "colloidosomes", a heterogeneous reaction takes place on the exposed surface of theExpand
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A supramolecular-hydrogel-encapsulated hemin as an artificial enzyme to mimic peroxidase.
A challenge in chemistry is an artificial enzyme that mimics the functions of the natural system but is simpler than proteins. The intensive development of artificial enzymes that use a variety ofExpand
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Studies on camptothecin. I. Effects of nucleic acid and protein synthesis.
The plant alkaloid camptothecin inhibits the synthesis of DNA and RNA in HeLa cells at concentrations that do not initially influence protein synthesis. DNA, isolated from cells inhibited byExpand
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Synthesis and cellular uptake of porphyrin decorated iron oxide nanoparticles-a potential candidate for bimodal anticancer therapy.
This paper reports the synthesis, characterization, and cellular uptake of the conjugate of porphyrin and iron oxide nanoparticles, which may lead to a bimodal anticancer agent that can be used inExpand
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Electrocatalytic four-electron reduction of oxygen to water by a highly flexible cofacial cobalt bisporphyrin
Dicobalt(II) cofacial bisporphyrins anchored by dibenzofuran (DPD) and xanthene (DPX) are efficient electrocatalysts for the four-electron reduction of oxygen to water despite their ca. 4 AExpand
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Probing the structure and stability of the tumor-localizing derivative of hematoporphyrin by reductive cleavage with LiAlH4.
A procedure involving the use of the reducing agent lithium aluminum hydride (LiAlH4) has been designed to explore the nature of the oligomer linkages in the tumor-localizing component ofExpand
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Some properties of a glutathione S-transferase from the larvae of Galleria mellonella
Abstract The glutathione transferase from Galleria mellonela has an estimated molecular weight of 41,000. It appears to be composed of two identical subunits of 25,000 molecular weight. Its substrateExpand
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CHEMISTRY OF HEMATOPORPHYRIN‐DERIVED PHOTOSENSITIZERS
Abstract The hematoporphyrin‐derived tumor‐localizing preparation HPD consists of porphyrin monomers, which are‘inactive’(not tumor‐localizing), and a dimer/oligomer fraction which is responsible forExpand
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