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The Vif accessory protein alters the cell cycle of human immunodeficiency virus type 1 infected cells.
The viral infectivity factor gene (vif) of HIV-1 increases the infectivity of viral particles by inactivation of cellular anti-viral factors, and supports productive viral replication in primary… Expand
Pleiotropic mutations in the HIV-1 matrix protein that affect diverse steps in replication.
The matrix domain of the Gag precursor protein, and the mature matrix protein, which is derived from processing of the Gag precursor, functions in several steps of the human immunodeficiency virus… Expand
The matrix region is responsible for the differential ability of two retroviruses to function as helpers for vector propagation.
We have investigated the ability of two related reticuloendotheliosis viruses to propagate a spleen necrosis virus (SNV) based retroviral vector in canine osticosarcoma (D17) cells.… Expand
Reply to — Apoptosis and HIV disease
Mapping of HIV-1 Determinants of Apoptosis in Infected T Cells☆☆☆
Abstract HIV-1 infection leads to death of CD4 + T cells in vivo and in vitro, although the mechanisms of this cell death are not well defined. We used flow cytometry to concurrently analyze… Expand
Mapping of HIV-1 Determinants of Apoptosis in Infected T Cells
HIV-1 infection leads to death of CD4(+) T cells in vivo and in vitro, although the mechanisms of this cell death are not well defined. We used flow cytometry to concurrently analyze infection and… Expand