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- Publications
- Influence
Interventions to Slow Aging in Humans: Are We Ready?
- V. Longo, A. Antebi, +27 authors L. Fontana
- Biology, Medicine
- Aging cell
- 22 April 2015
The workshop entitled ‘Interventions to Slow Aging in Humans: Are We Ready?’ was held in Erice, Italy, on October 8–13, 2013, to bring together leading experts in the biology and genetics of aging… Expand
A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people
- G. Colonna‐Romano, M. Bulati, A. Aquino, M. Pellicanó, C. Caruso
- Medicine
- Mechanisms of Ageing and Development
- 1 October 2009
The T cell branch of the immune system has been extensively studied in the elderly and it is known that the elderly have impaired immune function, mainly due to the chronic antigenic load that… Expand
Human immunosenescence: is it infectious?
- G. Pawelec, A. Akbar, C. Caruso, R. Solana, B. Grubeck‐Loebenstein, A. Wikby
- Biology, Medicine
- Immunological reviews
- 1 June 2005
Summary: Morbidity and mortality due to infectious disease is greater in the elderly than in the young, at least partly because of age‐associated decreased immune competence, which renders… Expand
Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: therapeutic implications.
- G. Candore, M. Bulati, +10 authors S. Vasto
- Medicine
- Rejuvenation research
- 12 May 2010
Alzheimer disease (AD) is a heterogeneous and progressive neurodegenerative disease, which in Western society mainly accounts for senile dementia. Today many countries have rising aging populations… Expand
Apoptosis and ageing
- M. Potestio, C. Caruso, F. Gervasi, G. Scialabba, G. Romano
- Biology, Medicine
- Mechanisms of Ageing and Development
- 15 May 1998
Stimulation of T cells from aged individuals leads to different kinds and/or size of responses if compared with the responses of T cells obtained from young individuals. In fact elderly is associated… Expand
B cells in the aged: CD27, CD5, and CD40 expression
- G. Colonna‐Romano, M. Bulati, A. Aquino, G. Scialabba, C. Caruso
- Biology, Medicine
- Mechanisms of Ageing and Development
- 1 April 2003
Ageing is characterized by numerous changes in lymphocyte subpopulations. In the present paper we have focused on B cells carrying the surface markers CD27, CD5 and CD40. CD27 is considered a marker… Expand
Inflammation, ageing and cancer
- S. Vasto, G. Carruba, D. Lio, G. Colonna‐Romano, C. Caruso
- Biology, Medicine
- Mechanisms of Ageing and Development
- 28 February 2009
Cancer is generally recognized as an age-related disease. In fact, incidence and mortality rates of most human cancers increase consistently with age up to 90 years, but they plateau and decline… Expand
B cell immunosenescence in the elderly and in centenarians.
- G. Colonna‐Romano, M. Bulati, +4 authors C. Caruso
- Biology, Medicine
- Rejuvenation research
- 28 April 2008
The elderly suffer from an increased susceptibility to infectious disease and cancer. Aging of the immune system contributes to this state of affairs due to immunosenescence. Because repeated… Expand
Aging, Longevity, Inflammation, and Cancer
- C. Caruso, D. Lio, L. Cavallone, C. Franceschi
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 1 December 2004
Abstract: Cancer rates increase sharply with age in both sexes, and the majority of cases of cancer occur in patients over the age of 65 years. However, the incidence and mortality for cancer level… Expand