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Characterization of surface layer proteins from different Clostridium difficile clinical isolates.
Data indicate that the presence of S-layer on C. difficile strains is common and that its glycoprotein subunits show a certain degree of heterogeneity.
A zinc-binding motif conserved in glyoxalase II, beta-lactamase and arylsulfatases.
The effects of pH and various salts upon the activity of a series of superoxide dismutases.
The CuZn superoxide dismutases (SODs) from ox, sheep, pig and yeast were investigated by pulse radiolysis in order to evaluate the role of electrostatic interactions between O2.- and SOD proteins in…
A Histidine-rich Metal Binding Domain at the N Terminus of Cu,Zn-Superoxide Dismutases from Pathogenic Bacteria
- A. Battistoni, F. Pacello, G. Rotilio
- Biology, ChemistryThe Journal of Biological Chemistry
- 10 August 2001
It is suggested that the histidine-rich N-terminal region constitutes a metal binding domain involved in metal uptake under conditions of metal starvation in vivo and enhances the protection offered by periplasmic Cu,Zn-superoxide dismutase toward phagocytic killing.
Functional and structural properties of the hemoglobin components from Italian sturgeon (Acipenser naccarii)
The structural and oxygen binding properties of Acipenser naccarii blood have been investigated and the functional properties seem to be related to the particular physiological needs dictated by the environmental characteristics.
Purification and characterization of the hemoglobin components of Adriatic sturgeon (Acipenser naccarii) blood
- M. E. Clementii, E. Cataldi, C. Capo, R. Petruzzelliz, E. Tellones, B. Giardina
- 1 September 1999
Summary The oxygen binding properties of Acipenser naccarii hemoglobins have been investigated, and were found not to differ significantly from those shown by blood, intact erythrocytes and…
Features of ceruloplasmin in the cerebrospinal fluid of Alzheimer’s disease patients
Results show that only a fraction of total copper is associated with CP in the CSF, at variance with serum, both in affected and in healthy individuals, and confirm that an impairment of copper metabolism occurs in their central nervous system.
Inactivation of cytochrome c oxidase by mutant SOD1s in mouse motoneuronal NSC‐34 cells is independent from copper availability but is because of nitric oxide
J. Neurochem. (2010) 112, 183–192.
Ceruloplasmin (2-D PAGE) Pattern and Copper Content in Serum and Brain of Alzheimer Disease Patients
The data show that AD patients have ceruloplasmin fragments of low molecular weight both in their serum and brain, contrary to healthy controls, and suggest a cerulplasmin fragmentation in the serum of AD patients.
Copper depletion increases the mitochondrial-associated SOD1 in neuronal cells
It is reported that treatment of human neuroblastoma cells SH-SY5Y with a specific copper chelator, triethylene tetramine (Trien) induces the decrease of intracellular copper level, paralleled by decreased activity of SOD1, and copper deficiency is not a factor which may worsen mitochondrial damage, which is one of the earliest events in fALS associated with mutant S OD1.