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Finite element models predict in vitro vertebral body compressive strength better than quantitative computed tomography.
It is established that QCT-based "voxel" finite element models are better predictors of vertebral compressive strength than QCT measures of bone mineral density with or without measures of cross-sectional area and offers great promise for improvement of clinical fracture risk assessment. Expand
Quantitative CT for determination of bone mineral density: a review.
  • C. Cann
  • Medicine
  • Radiology
  • 1 February 1988
The author reviewed this literature to provide both the historic perspective and current status of BMD measurement with CT, the physical and physiologic bases of the method, accuracy, reproducibility, radiation dose, and clinical utility. Expand
Precise measurement of vertebral mineral content using computed tomography.
A precise method of measuring vertebral mineral content by computed tomography has been developed and a long-term precision of 2.8% for mineral content has been obtained in excised vertebrae in a phantom simulating the human torso. Expand
Effect of bone distribution on vertebral strength: assessment with patient-specific nonlinear finite element analysis.
Three-dimensional quantitative computed tomographic studies of the lumbar spine were extended with finite element analysis (FEA) to include bone distribution in assessment of vertebral body strength, and a constant relationship between cortical and trabecular contributions was observed in patients with osteoporosis but not in control patients. Expand
Controlled Trial of Pamidronate in Children With Types III and IV Osteogenesis Imperfecta Confirms Vertebral Gains but Not Short‐Term Functional Improvement
A randomized controlled trial of q3m intravenous pamidronate in children with types III and IV OI yielded positive vertebral changes in DXA and geometry after 1 year of treatment, but no further significant improvement during extended treatment. Expand
Comparison of QCT-derived and DXA-derived areal bone mineral density and T scores
This study shows that results from QCT aBMD appropriately adjusted can be evaluated against NHANES reference data to diagnose osteoporosis. Expand
Quantitative Computed Tomography of Vertebral Spongiosa: A Sensitive Method for Detecting Early Bone Loss After Oophorectomy
The results indicate that spinal quantitative computed tomography provides a highly sensitive measurement of bone mineral loss after oophorectomy, that bone Mineral loss is five- to sevenfold greater from the spinal spongiosum than from the appendicular cortex, and that conjugated estrogen in doses of less than 0.6 mg/d are inadequate to prevent the vertebral mineral loss. Expand
CT-determined pulmonary artery diameters in predicting pulmonary hypertension.
Because CT allows precise, noninvasive measurement of the diameter of pulmonary arteries, it can be of value in detecting pulmonary hypertension and estimating mean pulmonary artery pressure. Expand
Brisk walking does not stop bone loss in postmenopausal women.
It is shown that a moderate brisk walking program of one year duration does not prevent the loss of spinal bone density in early-postmenopausal women. Expand
Carcinoma of the uterus: use of gadopentetate dimeglumine in MR imaging.
It is concluded that gadolinium enhancement adds to the accuracy of evaluation of endometrial carcinoma but is useful in only advanced cases of cervical carcinoma. Expand