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Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-α converting enzyme
The amyloid precursor protein (APP) of Alzheimer's disease is a transmembrane protein that is cleaved within its extracellular domain, liberating a soluble N-terminal fragment (sAPP alpha). PutativeExpand
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Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme.
The amyloid precursor protein (APP) of Alzheimer's disease is a transmembrane protein that is cleaved within its extracellular domain, liberating a soluble N-terminal fragment (sAPP alpha). PutativeExpand
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Th1 and Th2 cytokine mRNA profiles in childhood nephrotic syndrome: evidence for increased IL-13 mRNA expression in relapse.
Idiopathic nephrotic syndrome of childhood is thought to be associated with T lymphocyte dysfunction often triggered by viral infections, with the production of circulating factor(s) resulting inExpand
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Rock dynamics research related to cavern development for Ammunition storage
Abstract Researches on rock dynamics related to a cavern development project for ammunition storage in Singapore have been carried out. The researches include the study of dynamic properties of rockExpand
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Müllerian-inhibiting substance type II receptor expression and function in purified rat Leydig cells.
Müllerian-inhibiting substance (MIS), a gonadal hormone in the transforming growth factor-beta superfamily, induces Müllerian duct involution during male sexual differentiation. Mice with nullExpand
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Age- and sex-related changes in lymphocyte subpopulations of healthy Asian subjects: from birth to adulthood.
Flow cytometric analysis of lymphocyte subsets were evaluated in 391 healthy Asian subjects ranging in age from birth to 40 years. Lymphocyte subsets were analysed using specific monoclonalExpand
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Müllerian-Inhibiting Substance Type II Receptor Expression and Function in Purified Rat Leydig Cells.
Mullerian-inhibiting substance (MIS), a gonadal hormone in the transforming growth factor-β superfamily, induces Mullerian duct involution during male sexual differentiation. Mice with null mutationsExpand
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Chronic wound fluid suppresses proliferation of dermal fibroblasts through a Ras-mediated signaling pathway.
Wound fluid collected from chronic venous leg ulcers (chronic wound fluid (CWF)) has been shown to inhibit the growth of dermal fibroblasts by interfering with cell-cycle progression from G1 into SExpand
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bFGF-Induced Alterations in Cellular Markers of Senescence in Growth-rescued Fibroblasts from Chronic Venous Ulcer and Venous Reflux Patients
Fibroblasts cultured from the distal lower extremity of chronic venous insufficiency (CVI) patients exhibit characteristics of cellular senescence. Basic fibroblast growth factor (bFGF) has beenExpand
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Inflammatory response in bacterial meningitis: cytokine levels in the cerebrospinal fluid.
Inflammatory response plays an important role in the pathogenesis of cerebral injury in bacterial meningitis. In this study, we evaluated the cytokine levels of interleukin 1-beta (IL1 beta), tumourExpand
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