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Pathogenesis of systemic lupus erythematosus
The exact patho-aetiology of systemic lupus erythematosus (SLE) remains elusive. An extremely complicated and multifactorial interaction among various genetic and environmental factors is probably… Expand
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
Systemic lupus erythematosus is a complex and potentially fatal autoimmune disease, characterized by autoantibody production and multi-organ damage. By a genome-wide association study (320 patients… Expand
Risk factors for avascular bone necrosis in systemic lupus erythematosus.
OBJECTIVE To study the predictive factors for avascular necrosis (AVN) of bone in patients with systemic lupus erythematosus (SLE). METHOD The records of 38 SLE patients who developed clinically… Expand
Prevalence of atherosclerotic risk factors and the metabolic syndrome in patients with chronic inflammatory arthritis
- C. C. Mok, G. Ko, L. Y. Ho, K. Yu, P. Chan, C. H. To
- Arthritis care & research
- 1 February 2011
To evaluate the prevalence of the metabolic syndrome in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA).
Accuracy of anti-ribosomal P protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus: an international meta-analysis.
OBJECTIVE To quantitatively evaluate the diagnostic accuracy of antibodies to ribosomal P proteins (anti-P) for neuropsychiatric systemic lupus erythematosus (NPSLE) in general, for psychosis, mood… Expand
Tacrolimus for induction therapy of diffuse proliferative lupus nephritis: an open-labeled pilot study.
BACKGROUND Tacrolimus is a relatively new calcineurin inhibitor that has been increasingly used in transplant medicine. The objective of the current work is to report our preliminary experience with… Expand
Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus.
OBJECTIVE To study the genetic association of interleukin-10 (IL-10) promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus (SLE), and to investigate possible… Expand
A prospective study of survival and prognostic indicators of systemic lupus erythematosus in a southern Chinese population.
OBJECTIVES To study the survival rate and prognostic indicators of systemic lupus erythematosus (SLE) in a southern Chinese population. METHODS One hundred and eighty-six patients with SLE… Expand
Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up
Objective To compare the efficacy of tacrolimus (TAC) and mycophenolate mofetil (MMF) for the initial therapy of lupus nephritis (LN). Study design This is an open randomised controlled parallel… Expand
Clinical characteristics and outcome of southern Chinese males with systemic lupus erythematosus
The aims were to study the gender differences in clinical manifestations, disease course and organ damage in systemic lupus erythematosus (SLE). Clinical manifestations, autoantibody profile,… Expand