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A traditional Chinese herbal preparation, Er-Zhi-Wan, prevent ovariectomy-induced osteoporosis in rats.
ETHNOPHARMACOLOGICAL RELEVANCE Er-Zhi-Wan (EZW), a classic Chinese formulation, which contains Fructus Ligustri Lucidi (FLL) and Herba Ecliptae (HE). EZW is widely used to prevent and treat variousExpand
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Excentral cleavage of β-carotene in vivo in a healthy man
Background: Excentral cleavage of -carotene to retinoids and apocarotenoids occurs in vitro and in animal models. Whether it occurs in humans is unclear. Objective: We tested the hypothesis ofExpand
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Ergosta-4,6,8(14),22-tetraen-3-one induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
BACKGROUND Mushrooms have been used in Asia as traditional foods and medicines for a long time. Ergosta-4,6,8(14),22-tetraen-3-one (ergone) is one of the well-known bioactive steroids, which existsExpand
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A feasibility study quantifying in vivo human α-tocopherol metabolism
BACKGROUND Quantitation of human vitamin E metabolism is incomplete, so we quantified RRR- and all-rac-alpha-tocopherol metabolism in an adult. OBJECTIVE The objective of the study was to quantifyExpand
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LC Method for the Determination of Rhaponticin in Rat Plasma, Faeces and Urine for Application to Pharmacokinetic Studies
A simple liquid chromatography (LC) method has been developed and validated to determine rhaponticin in rat plasma, faeces and urine. Chromatographic separation was achieved through mobile phaseExpand
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A minute dose of 14C-{beta}-carotene is absorbed and converted to retinoids in humans.
Our objective was to quantify the absorption and conversion to retinoids of a 1.01-nmol, 3.7-kBq oral dose of (14)C-beta-carotene in 8 healthy adults. The approach was to quantify, using AMS, theExpand
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Kinetics of 14C distribution after tracer dose of 14C-lutein in an adult woman
Lutein is an oxygenated carotenoid (xanthophyll) found in dark green leafy vegetables. High intakes of lutein may lower the risk of age-related macular degeneration. Current understanding of humanExpand
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Excentral cleavage of beta-carotene in vivo in a healthy man.
BACKGROUND Excentral cleavage of beta-carotene to retinoids and apocarotenoids occurs in vitro and in animal models. Whether it occurs in humans is unclear. OBJECTIVE We tested the hypothesis ofExpand
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