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NAFLD: a multisystem disease.
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in Western countries that is predicted to become also the most frequent indication for liver… Expand
Omega-3 fatty acids, hepatic lipid metabolism, and nonalcoholic fatty liver disease.
Long-chain omega-3 fatty acids belong to a family of polyunsaturated fatty acids that are known to have important beneficial effects on metabolism and inflammation. Such effects may confer a benefit… Expand
Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?
Non-alcoholic fatty liver disease (NAFLD) affects up to a third of the population worldwide and may confer increased cardiometabolic risk with consequent adverse cardiovascular outcomes independent… Expand
Global epidemiology of nonalcoholic fatty liver disease: Meta‐analytic assessment of prevalence, incidence, and outcomes
We appreciated Dr. Younossi and colleagues’ metaanalysis of the global prevalence, incidence, progression, and outcomes of nonalcoholic fatty liver disease (NAFLD). We believe that the topic is… Expand
Depot-related gene expression in human subcutaneous and omental adipocytes.
Human omental adipocytes display a range of biochemical properties that distinguish them from adipocytes of subcutaneous origin. However, information about site-related gene expression in human fat… Expand
Maternal high‐fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression
Nonalcoholic fatty liver disease (NAFLD) describes an increasingly prevalent spectrum of liver disorders associated with obesity and metabolic syndrome. It is uncertain why steatosis occurs in some… Expand
Nonalcoholic Fatty Liver Disease and Risk of Incident Type 2 Diabetes: A Meta-analysis
OBJECTIVE Several studies have explored the impact of nonalcoholic fatty liver disease (NAFLD) on risk of incident type 2 diabetes. However, the extent to which NAFLD may confer risk of incident… Expand
Non-alcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-analysis.
- G. Targher, C. Byrne, A. Lonardo, G. Zoppini, C. Barbui
- Journal of hepatology
- 1 September 2016
BACKGROUND & AIMS There have been many studies of the effects of non-alcoholic fatty liver disease (NAFLD) and the risk of cardiovascular disease (CVD), but these have produced conflicting results.… Expand
Nonalcoholic fatty liver disease and chronic vascular complications of diabetes mellitus
Nonalcoholic fatty liver disease (NAFLD) and diabetes mellitus are common diseases that often coexist and might act synergistically to increase the risk of hepatic and extra-hepatic clinical… Expand
Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD).
Non-alcoholic fatty liver disease (NAFLD) is associated with diabetes, obesity and insulin resistance. The pathogenesis of NAFLD is complex, but modulation of the activities of transcription factors… Expand