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Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cells
TLDR
It is ironic that the gE-gI complex, usually considered an IgG Fc receptor, may, through its ability to mediate cell-to-cell spread, actually protect HSV from IgG in a manner different than previously thought.
Poxviruses and immune evasion.
TLDR
Because of their anti-inflammatory nature, many of these poxvirus proteins hold promise as potential therapeutic agents for acute or chronic inflammatory conditions.
Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes
TLDR
The re-analysis of genomes within the Iridoviridae family provides a unifying framework to understand the biology of these viruses, and further re-defining the core set of iridovirus genes will continue to lead to a better understanding of the phylogenetic relationships between individual irids.
Herpes Simplex Virus gE/gI Sorts Nascent Virions to Epithelial Cell Junctions, Promoting Virus Spread
TLDR
It is shown that HSV particles are specifically sorted to cell junctions and few virions reach the apical surfaces of polarized epithelial cells and gE/gI participates in this sorting.
FROG VIRUS 3-LIKE INFECTIONS IN AQUATIC AMPHIBIAN COMMUNITIES
TLDR
A simple model of FV3/FV3-like virus transmission postulates that, in aquatic amphibian communities, transmission of the virus occurs between anuran and urodele species, with ambystomatid salamanders the most likely reservoir for the ranavirus in this study.
Role of mannose-6-phosphate receptors in herpes simplex virus entry into cells and cell-to-cell transmission
TLDR
It appears that M-6-P residues and MPRs are required for efficient transmission of HSV between cells, a process which differs in some respects from entry of exogenous virus particles.
Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors
TLDR
Interestingly, the amino acid sequence of ORFV CBP more closely resembles the granulocyte–macrophage colony-stimulating factor/IL-2 inhibitory factor protein as a highly diverged, but related, member of the CBP-II protein family.
A secreted high-affinity inhibitor of human TNF from Tanapox virus
TLDR
The 2L protein can inhibit human TNF from binding to TNF receptors I and II as well as block TNF-induced cytolysis and offers a unique strategy with which to modulate TNF activity.
Herpes simplex virus glycoprotein D acquires mannose 6-phosphate residues and binds to mannose 6-phosphate receptors.
Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration
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