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Pathologic and clinical findings to predict tumor extent of nonpalpable (stage T1c) prostate cancer.
OBJECTIVES We examined preoperative clinical and pathologic parameters in men with clinical stage T1c disease who underwent radical prostatectomy and correlated these findings with the pathologicExpand
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Effect of preoperative biofeedback/pelvic floor training on continence in men undergoing radical prostatectomy.
OBJECTIVES To determine whether preoperative biofeedback training improves urinary continence overall or the rate of return of continence in men undergoing radical prostatectomy. METHODS OneExpand
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Overexpression of transforming growth factor β1 in malignant prostate cells is partly caused by a runaway of TGF-β1 auto-induction mediated through a defective recruitment of protein phosphatase 2A
OBJECTIVES To elucidate the mechanism of transforming growth factor (TGF)-β1 overexpression in prostate cancer cells. METHODS Malignant (PC3, DU145) and benign (RWPE1, BPH1) prostate epithelialExpand
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Molecular biology of bladder cancer.
Recent studies have provided the first clues as to the molecular mechanisms responsible for bladder carcinogenesis. Cytogenetic and molecular studies have demonstrated nonrandom changes ofExpand
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Robotic radical prostatectomy in patients with high-risk disease: a review of short-term outcomes from a high-volume center.
PURPOSE Patients with high-risk prostate cancer have historically been treated with multimodal therapy and considered poor candidates for minimally invasive surgery. We reviewed our experiences withExpand
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Spontaneous benign prostatic hyperplasia in the beagle. Age-associated changes in serum hormone levels, and the morphology and secretory function of the canine prostate.
This paper is a cross-sectional study of spontaneous benign prostatic hyperplasia (BPH) in a single canine species. The effects of aging and hormonal changes on the growth, histology, and glandularExpand
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Radical prostatectomy for impalpable prostate cancer: the Johns Hopkins experience with tumors found on transurethral resection (stages T1A and T1B) and on needle biopsy (stage T1C).
We review the pathological findings of impalpable prostate cancer detected by transurethral resection (stages T1a and T1b) and needle biopsy (stage T1c). The short-term (4 years) and long-term (8 toExpand
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Pelvic lymphadenectomy during robot-assisted radical prostatectomy: Assessing nodal yield, perioperative outcomes, and complications.
OBJECTIVES To describe our pelvic lymphadenectomy (PLND) technique during robot-assisted radical prostatectomy and to evaluate the nodal yield and perioperative outcomes. PLND is commonly performedExpand
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Characterization of an N-methyl-N-nitrosourea-induced autochthonous rat bladder cancer model.
Cohorts of 4- to 5-wk-old female Fischer 344 rats received four biweekly 1.5-mg doses of N-methyl-N-nitrosourea (MNU) intravesically and were sacrificed at various intervals. By 13 wk afterExpand
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Germline mutations in ATM and BRCA1/2 distinguish risk for lethal and indolent prostate cancer and are associated with early age at death
Rong Na a,b,y, S. Lilly Zheng b,c,y, Misop Han d,y, Hongjie Yu , Deke Jiang , Sameep Shah , Charles M. Ewing , Liti Zhang , Kristian Novakovic b [5_TD$DIFF], Jacqueline Petkewicz [5_TD$DIFF],Expand
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