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Application of the static dephasing regime theory to superparamagnetic iron‐oxide loaded cells
TLDR
The relaxation rates of iron‐oxide nanoparticles compartmentalized within cells were studied and found to satisfy predictions of the static dephasing (SD) regime theory, consistent with theoretical estimates of the required mass of iron per compartment needed to guarantee SD‐regime‐dominant relaxivity. Expand
Detection threshold of single SPIO‐labeled cells with FIESTA
TLDR
The results of this work will aid in the design of cellular imaging experiments by defining the lower limit of SPIO labeling required for single cell detection at any given resolution and SNR. Expand
High field balanced-SSFP fMRI: A BOLD technique with excellent tissue sensitivity and superior large vessel suppression
TLDR
This paper proposes the use of balanced SSFP at high field (4T) using on-resonance acquisitions without shimming in regions of interest to the edge of the b-SSFP transition band, and shows b- SSFP fMRI acquisitions have far greater sensitivity to the BOLD mechanism than gradient echo acquisitions with matched TR/TE. Expand
Compressed sensing reconstruction improves sensitivity of variable density spiral fMRI
TLDR
This study explored whether fMRI sensitivity can be improved through the use of compressed sensing (CS) reconstruction of variable density spiral fMRI. Expand
In Vivo Detection of Human TRPV6-Rich Tumors with Anti-Cancer Peptides Derived from Soricidin
TLDR
Molecular imaging methods that demonstrate the in vivo diagnostic potential of S OR-C13 and SOR-C27 to target tumor sites in mice bearing ovarian or prostate tumors suggest that these novel peptides may provide an avenue to deliver diagnostic and therapeutic reagents directly to TRPV6-rich tumors. Expand
Differences in perceived shape from shading correlate with activity in early visual areas
TLDR
A three-dimensional functional magnetic resonance imaging (fMRI) study at 1.5 Tesla found significantly greater activation in area V1 and neighbouring low-level visual areas of cortex when subjects viewed displays that led to weak and unstable depth percepts than when they viewed displays That led to strong and stabledepth percepts. Expand
Gradient‐induced acoustic and magnetic field fluctuations in a 4T whole‐body MR imager
TLDR
The results show the existence of discrete resonances in both acoustic and uniform magnetic field fluctuation spectra, while gradient magnetic field fluctuations spectra show no such resonances, which implies that these phenomena are correlated, and that the trapezoidal impulse flat‐top width may be used as a way to suppress both acoustic noise and uniform Magnetic field oscillations. Expand
Relaxometry model of strong dipolar perturbers for balanced‐SSFP: Application to quantification of SPIO loaded cells
TLDR
This work develops a technique to quantify superparamagnetic iron‐oxide (SPIO) loaded cells using fully balanced steady state free precession (b‐SSFP) imaging and believes this model can be used to facilitate the generation of quantitative maps of targeted cell populations. Expand
Confirming white matter fMRI activation in the corpus callosum: Co-localization with DTI tractography
TLDR
Findings provide the foundation for future work combining white matter fMRI and DTI tractography to study brain connectivity and confirm that the activated regions of the corpus callosum were structurally connected to the functional network of gray matter regions involved in the task. Expand
Asymmetric spin‐echo (ASE) spiral improves BOLD fMRI in inhomogeneous regions
TLDR
A new multiple spiral acquisition technique was developed, in which the later spiral acquisitions are acquired asymmetrically with the peak of a spin‐echo causing increased R2‐weighting but matched R2′‐ weighting, which allows for recovery of BOLD activation in areas of SFG without sacrificing the CNR over the whole brain. Expand
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