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Molecular cloning and protein structure of a human blood group Rh polypeptide.
TLDR
Hydropathy analysis and secondary structure predictions suggest the presence of 13 membrane-spanning domains, indicating that the Rh polypeptide is highly hydrophobic and deeply buried within the phospholipid bilayer.
Vascular endothelial growth factor is modulated in vascular muscle cells by estradiol, tamoxifen, and hypoxia.
TLDR
E2 induction of VEGF expression in human venous muscle cells [smooth muscle cells from human saphenous veins; HSVSMC] expressing both ER-alpha and ER-beta estrogen receptors is reported, suggesting E2 modulation of V EGF effects in angiogenesis, vascular permeability, and integrity.
Rabbit Antithymocyte Globulin Inhibits Monocyte-Derived Dendritic Cells Maturation In Vitro and Polarizes Monocyte-Derived Dendritic Cells Towards Tolerogenic Dendritic Cells Expressing Indoleamine
Background. Rabbit antithymocyte globulin (rATG) is a polyclonal mixture of immunoglobulin (Ig) G. It is used to prevent graft rejection and also graft versus host disease after transplantation. Its
Characterization of the blood group Kell (K1) antigen with a human monoclonal antibody.
TLDR
Immunoprecipitation analysis showed that the K1 antigen is carried by a 93 Kd glycoprotein containing several cysteine residues, and approximately six N-glycosidically linked sugar chains but no detectable O-linked sugar, and it is suggested that the 120-Kd component represents a heterodimer of the 93- and 32-kd proteins covalently linked by disulfide bridge(s).
Two-dimensional iodopeptide mapping demonstrates that erythrocyte Rh D, c, and E polypeptides are structurally homologous but nonidentical.
TLDR
The data indicate that the erythrocyte Rh D, c, and E antigens are carried by homologous but distinct molecular species; c and E appear more closely related to each other than to D.
Gerbich reactivity in 4.1(—) hereditary elliptocytosis and protein 4.1 level in blood group Gerbich deficiency
The membrane polypeptide composition and the blood group Gerbich phenotype of red cells from 4.1(–) hereditary elliptocytic patients and from Gerbich‐negative donors, who display two unrelated
Human monoclonal antibody against Rh(D) antigen: partial characterization of the Rh(D) polypeptide from human erythrocytes.
TLDR
Immune precipitation studies and binding studies indicate that the monoclonal and the polyclonal human anti-Rh(D) behave similarly and suggest that the Rh( D) polypeptide is loosely bound to the skeleton, since less than or equal to 80% can be solubilized from the membrane.
FT-IR spectroscopy as an emerging method for rapid characterization of microorganisms.
TLDR
Statistical methods such as principal component analysis and cluster analysis were used to analyze ATR-FT-IR spectra obtained from bacterial whole cells and are conclusive in showing that they can discriminate and classify bacterial strains of clinical origin exhibiting different resistance mechanisms.
Involvement of Rh blood group polypeptides in the maintenance of aminophospholipid asymmetry.
TLDR
Immunoprecipitated Rh polypeptides were found to be labeled with the aminophospholipid translocase markers, suggesting that Rh proteins are involved in the transbilayer movement of PS.
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