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An OHSS-Free Clinic by segmentation of IVF treatment.
The syndrome can be erased by applying ovarian stimulation using the combination of GnRH antagonist with GnRH agonist to trigger ovulation, and the strategy is to freeze all of the oocytes or embryos for later use.
Progesterone rise on HCG day in GnRH antagonist/rFSH stimulated cycles affects endometrial gene expression.
Live birth rates following natural cycle IVF in women with poor ovarian response according to the Bologna criteria.
The trial suggests that although natural cycle IVF is a promising treatment option for younger normal responders, its potential is very limited to poor ovarian responders as described by the Bologna criteria, irrespective of patient's age.
Conventional ovarian stimulation and single embryo transfer for IVF/ICSI. How many oocytes do we need to maximize cumulative live birth rates after utilization of all fresh and frozen embryos?
A large cohort analysis of retrospective data from January 2009 to December 2013 in a tertiary medical centre, at the Centre for Reproductive Medicine at the University Hospital of Brussels, finds that the number of oocytes retrieved does not affect LBR in the fresh IVF cycle, but the higher the oocyte yield, the better the probability of achieving a live birth, and biases related to retrospective design cannot be excluded.
Identification and evaluation of the microbiome in the female and male reproductive tracts
An overview of the currently used techniques and the reported microbiota compositions in the different anatomical parts of the female and male reproductive tracts since the introduction of NGS in 2005 is provided to understand and determine the interactions and roles of the different microbes necessary for successful reproduction.
Frozen embryo transfer: a review on the optimal endometrial preparation and timing
A standardized timing strategy based on the current available evidence which could assist in the harmonization and comparability of clinic practice and future trials is proposed, with special attention to the timing of the embryo transfer.
A fresh look at the freeze-all protocol: a SWOT analysis.
- C. Blockeel, P. Drakopoulos, S. Santos-Ribeiro, N. Polyzos, H. Tournaye
- BiologyHuman reproduction
- 1 March 2016
A SWOT (strengths, weaknesses, opportunities and threats) analysis sheds light on the different aspects of the 'freeze-all' strategy with the segmentation of IVF treatment.
Consistent high clinical pregnancy rates and low ovarian hyperstimulation syndrome rates in high-risk patients after GnRH agonist triggering and modified luteal support: a retrospective multicentre…
In women who are undergoing ovarian stimulation and who develop an excessive ovarian response, the use of a GnRH agonist trigger combined with modified luteal support can provide the opportunity to proceed to fresh embryo transfer with adequate clinical pregnancy rates.
Influence of cell loss after vitrification or slow-freezing on further in vitro development and implantation of human Day 3 embryos.
It is not proved that vitrified embryos are more viable than slowly frozen embryos in terms of pregnancy outcome, but vitrification yields higher survival rates, better overnight development and higher transfer rates per embryo warmed.