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Autoimmune Thyroid Diseases in Children
The two major autoimmune thyroid diseases (ATDs) include Graves' disease (GD) and autoimmune thyroiditis (AT); both of which are characterized by infiltration of the thyroid by T and B cells reactiveExpand
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Children with Prader-Willi syndrome exhibit more evident meal-induced responses in plasma ghrelin and peptide YY levels than obese and lean children.
BACKGROUND AND AIMS Ghrelin is an orexigenic 28-amino acid peptide produced by the stomach. Circulating ghrelin levels rise shortly before and fall shortly after every meal. Peptide YY (PYY), anExpand
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Basal insulin supplementation in Type 1 diabetic children: A long-term comparative observational study between continuous subcutaneous insulin infusion and glargine insulin
No long-term data are available on the efficacy of glargine insulin in comparison with continuous sc insulin infusion (CSII) in children and adolescents affected by Type 1 diabetes (T1D). Our aim wasExpand
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Endocrine Implications of Neurofibromatosis 1 in Childhood
In 1882, von Recklinghausen described a group of patients with multiple tumors arising from the ‘endoneurium' of peripheral nerves, and called them ‘neurofibromas'. The term von RecklinghausenExpand
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Metabolic syndrome and diabetes mellitus in childhood cancer survivors.
BACKGROUND The survival of children with cancer has grown considerably in recent years resulting in a marked increase of endocrine complications. increasingly recognized problems are metabolicExpand
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Clinical effects of early treatment with insulin glargine in patients with cystic fibrosis and impaired glucose tolerance
Diabetes mellitus is an increasing complication of cystic fibrosis (CF), as a result of the improved life expectancy. There is clear association between diabetes and increased morbidity andExpand
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The Gly972-->Arg IRS-1 variant is associated with type 1 diabetes in continental Italy.
The Arg(972) insulin receptor substrate-1 (IRS-1) variant has been hypothesized to play a role in pancreatic beta-cell stimulus-coupled insulin secretion and survival. We analyzed the relationsExpand
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Maintenance of a normal meal-induced decrease in plasma ghrelin levels in children with Prader-Willi syndrome.
Ghrelin is a 28-amino acid peptide recently identified in the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHS-R1a). Ghrelin is a potent stimulator of GH secretion.Expand
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Menarche in type 1 diabetes is still delayed despite good metabolic control.
OBJECTIVE To analyze the age at menarche of girls with type 1 diabetes (T1D) who were diagnosed with the disease before puberty and compare it with that of an age-matched group of normal girls.Expand
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The effects of calcitriol and nicotinamide on residual pancreatic β‐cell function in patients with recent‐onset Type 1 diabetes (IMDIAB XI)
Background  A number of recent studies underline the importance of vitamin D in the pathogenesis of Type 1 diabetes (T1D).
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