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Diversity of the Human Intestinal Microbial Flora
The human endogenous intestinal microflora is an essential “organ” in providing nourishment, regulating epithelial development, and instructing innate immunity; yet, surprisingly, basic featuresExpand
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Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology.
The discovery of a series of genetic and serological markers associated with disease susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an integrated classificationExpand
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Infliximab maintenance therapy for fistulizing Crohn's disease.
BACKGROUND Infliximab, a monoclonal antibody against tumor necrosis factor, is an effective maintenance therapy for patients with Crohn's disease without fistulas. It is not known whether infliximabExpand
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The Epidemiology of Inflammatory Bowel Disease in Canada: A Population-Based Study
BACKGROUND:Previously, we have demonstrated a high incidence and prevalence of Crohn's disease (CD) and ulcerative colitis (UC) in the Canadian province of Manitoba. However, the epidemiology ofExpand
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Cancer risk in patients with inflammatory bowel disease
The objective of the current study was to determine the incidence of cancer among persons with inflammatory bowel disease (IBD) and to compare these incidence rates with those of the non‐IBDExpand
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The prevalence of extraintestinal diseases in inflammatory bowel disease: a population-based study
OBJECTIVE:The aim of this study was to determine the prevalence of the major extraintestinal manifestations of inflammatory bowel disease (IBD) and their relation to disease diagnosis andExpand
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Epidemiology of Crohn's disease and ulcerative colitis in a central Canadian province: a population-based study.
The aim of this study was to assess the accuracy and utility of administrative health data in identifying persons with inflammatory bowel disease on a population basis and to determine the incidenceExpand
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The incidence of deep venous thrombosis and pulmonary embolism among patients with inflammatory bowel disease: a population-based cohort study.
BACKGROUND There is an impression mostly from specialty clinics that patients with inflammatory bowel disease (IBD) have an increased risk of venous thromboembolic disorders. Our aim was to determineExpand
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A Population-Based Case Control Study of Potential Risk Factors for IBD
BACKGROUND:We aimed to pursue potential etiological clues to Crohn's disease (CD) and ulcerative colitis (UC) through a population-based case control survey study.METHODS:Cases with CD (n = 364) andExpand
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Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis?
The recommended approach to the increased risk of colorectal carcinoma in ulcerative colitis has been colonoscopic surveillance rather than prophylactic colectomy. This strategy is based on theExpand
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