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LAT2, a New Basolateral 4F2hc/CD98-associated Amino Acid Transporter of Kidney and Intestine*
Glycoprotein-associated amino acid transporters (gpaAT) are permease-related proteins that require heterodimerization to express their function. So far, four vertebrate gpaATs have been shown toExpand
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Luminal heterodimeric amino acid transporter defective in cystinuria.
Mutations of the glycoprotein rBAT cause cystinuria type I, an autosomal recessive failure of dibasic amino acid transport (b(0,+) type) across luminal membranes of intestine and kidney cells. HereExpand
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Functional Cooperation of Epithelial Heteromeric Amino Acid Transporters Expressed in Madin-Darby Canine Kidney Cells*
The heteromeric amino acid transporters b0,+AT-rBAT (apical), y+LAT1-4F2hc, and possibly LAT2-4F2hc (basolateral) participate to the (re)absorption of cationic and neutral amino acids in the smallExpand
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Apical heterodimeric cystine and cationic amino acid transporter expressed in MDCK cells.
  • C. Bauch, F. Verrey
  • Medicine, Biology
  • American journal of physiology. Renal physiology
  • 1 July 2002
The luminal uptake of L-cystine and cationic amino acids by (re)absorptive epithelia, as found in the small intestine and the proximal kidney tubule, is mediated by the transport system b(0,+), whichExpand
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Mercuric conjugates of cysteine are transported by the amino acid transporter system b(0,+): implications of molecular mimicry.
Humans and other mammals continue to be exposed to various forms of mercury in the environment. The kidneys, specifically the epithelial cells lining the proximal tubules, are the primary targetsExpand
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Isoform specificity of human Na(+), K(+)-ATPase localization and aldosterone regulation in mouse kidney cells.
Short-term aldosterone coordinately regulates the cell-surface expression of luminal epithelial sodium channels (ENaC) and of basolateral Na(+) pumps (Na(+), K(+)-ATPase alpha1-beta1) inExpand
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Synthesis, Conformational Properties, and Immunogenicity of a Cyclic Template-Bound Peptide Mimetic Containing an NPNA Motif from the Circumsporozoite Protein of Plasmodium falciparum
The immunodominant central portion of the circumsporozoite (CS) surface protein of the malaria parasite Plasmodium falciparum contains a tetrapeptide motif, Asn-Pro-Asn-Ala (NPNA), tandemly repeatedExpand
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A metal-free catalytic intramolecular hydrosilylation
A metal-free catalytic intramolecular hydrosilylation reaction is reported. The key intermediates in the catalytic cycle are silyl cationic species. The reaction is used to produce 2-silanorbornanesExpand
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Fecal bacterial activity in symptomatic carbohydrate malabsorption: effect on the fecal short-chain fatty acid ratio.
BACKGROUND It is still not clear why only some patients with carbohydrate malabsorption experience symptoms. In a previous study on healthy fructose malabsorbers an increased degradation of fructoseExpand
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