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Endometrial Carcinomas: A Review Emphasizing Overlapping and Distinctive Morphological and Immunohistochemical Features
This review focuses on the most common diagnostic pitfalls and helpful morphologic and immunohistochemical markers in the differential diagnosis between the different subtypes of endometrialExpand
Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium
The data shows that sirtuins are deregulated in EC, and the diversity of expression patterns observed suggests that sIRTuins may have distinctive roles in endometrial cancer similarly to what has been described in other cancer models. Expand
Pathologic Findings in Prophylactic and Nonprophylactic Hysterectomy Specimens of Patients With Lynch Syndrome
The clinicopathologic features of a series of 70 LS patients who underwent either PH or nonprophylactic hysterectomy (NPH) at 3 tertiary referral centers are reported, finding that some patients harbor preneoplastic or neoplastic conditions treatable at an early stage. Expand
Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas
It is recommended that patients with these neoplasias should be offered BRCA1/BRCA2 genetic testing and it is shown that it is feasible to test for founder mutations in archival tumor tissue. Expand
Massive right atrial myxoma presenting as syncope and exertional dyspnea: case report
Three-dimensional echocardiography proved useful in surgery planning, allowing a better definition of the tumor outline and attachment, and illustrates the influence of myxoma's size, position and mobility as well as patient's body posture and respiration to the development of signs and symptoms. Expand
Factors associated with mortality and length of stay in the Oporto burn unit (2006-2009).
The characteristics before and after the creation of the burn unit, as well as the similarities and differences with the published data of other national and international burn units, are analysed. Expand
Gynaecological neoplasms in common familial syndromes (Lynch and HBOC).
Hereditary syndromes are well recognised, but the prognostic and predictive implications of these molecular phenotypes have only recently been elucidated and these aspects will finally ensure that molecular screening may become standard of care. Expand
Reproducibility of lymphovascular space invasion (LVSI) assessment in endometrial cancer
A study is designed to evaluate interobserver agreement in discriminating true LVSI from LVSI mimics and reproducibility of grading extent of LVSI in EC. Expand
A stereological study on organelle distribution in human oocytes at prophase I
This study used a stereological approach to quantify the distribution of organelles in oocytes at prophase I (GV) and described in GV oocytes very large vesicles of the smooth endoplasmic reticulum (SER), vesicle containing zona pellucida-like materials and coatedvesicles. Expand
Endometrial endometrioid adenocarcinoma associated with primitive neuroectodermal tumour of the uterus: a poor prognostic subtype of uterine tumours
Regardless of the detection of an EWSR1 rearrangement, the presence of a neuroectodermal differentiation component in these rare uterine tumours is a marker of aggressive behaviour, and its presence should be highlighted in the diagnosis. Expand