• Publications
  • Influence
Four zona pellucida glycoproteins are expressed in the human.
BACKGROUND The zona pellucida (ZP) is an extracellular glycoprotein matrix which surrounds all mammalian oocytes. Recent data have shown the presence of four human zona genes (ZP1, ZP2, ZP3 and ZPB).Expand
  • 266
  • 21
  • PDF
Stimulation of Human Spermatozoa with Progesterone Gradients to Simulate Approach to the Oocyte
Progesterone is present at micromolar concentrations in the cumulus matrix, which surrounds mammalian oocytes. Exposure of human spermatozoa to a concentration gradient of progesterone (0–3 μm) toExpand
  • 164
  • 15
A survey of assisted reproductive technology births and imprinting disorders.
BACKGROUND Genomic imprinting is an epigenetic process in which allele-specific gene expression is dependent on the parental inheritance. Although only a minority of human genes are imprinted, thoseExpand
  • 97
  • 14
  • PDF
Sperm proteome mapping of a patient who experienced failed fertilization at IVF reveals altered expression of at least 20 proteins compared with fertile donors: case report.
The aim of this study was to compare the sperm protein expression profile (proteome map) from a patient who experienced failed fertilization at IVF with fertile controls. One patient and threeExpand
  • 141
  • 11
  • PDF
Ca2+ Signals Generated by CatSper and Ca2+ Stores Regulate Different Behaviors in Human Sperm*
Background: Ca2+ signals, elicited by cues from the oocyte and female tract, regulate human sperm behavior. Results: CatSper channel activation (flagellum) and Ca2+ store mobilization (neck) causedExpand
  • 114
  • 11
  • PDF
Ca2+-stores in sperm: their identities and functions.
Intracellular Ca2+ stores play a central role in the regulation of cellular [Ca2+](i) and the generation of complex [Ca2+] signals such as oscillations and waves. Ca2+ signalling is of particularExpand
  • 161
  • 9
  • PDF
A Practical Guide to Basic Laboratory Andrology
A Practical Guide to Basic Laboratory Andrology - Libros de Medicina - Fertilidad y embarazo - 39,42
  • 69
  • 9
  • PDF
[Ca2+]i signalling in sperm — making the most of what you've got
Thanks to a worrying decrease in male fertility, understanding how sperm 'work' is a matter both of interest and great importance. Sperm of all animals detect various environmental cues. TheExpand
  • 238
  • 8
Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications--a position report.
This article reports the results of the most recent in a series of EHSRE workshops designed to synthesize the current state of the field in Andrology and provide recommendations for future work (forExpand
  • 262
  • 8
  • PDF
When and how should new technology be introduced into the IVF laboratory?
There are many examples in assisted reproduction technology, where new technology and methods have been introduced into the clinical setting without appropriate development and evidence-basedExpand
  • 132
  • 7
  • PDF