International Study to Evaluate PCR Methods for Detection of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients
- A. Schijman, M. Bisio, Janis Ladzins
- MedicinePLoS Neglected Tropical Diseases
- 1 January 2011
This study represents a first crucial step towards international validation of PCR procedures for detection of T. cruzi in human blood samples by an external quality evaluation.
Severe Acquired Toxoplasmosis in Immunocompetent Adult Patients in French Guiana
- B. Carme, F. Bissuel, M. Dardé
- MedicineJournal of Clinical Microbiology
- 1 November 2002
ABSTRACT The most common presentation of symptomatic postnatally acquired toxoplasmosis in immunocompetent patients is painless cervical adenopathy. Acute visceral manifestations are associated in…
Trypanosoma cruzi I genotypes in different geographical regions and transmission cycles based on a microsatellite motif of the intergenic spacer of spliced-leader genes.
- C. Cura, A. Mejía-Jaramillo, A. Schijman
- BiologyInternational Journal of Parasitology
- 1 December 2010
Integrate study of a Bolivian population infected by Trypanosoma cruzi, the agent of Chagas disease.
- S. Brenière, M. Bosseno, M. Hontebeyrie
- MedicineMemórias do Instituto Oswaldo Cruz
- 1 April 2002
A cross section of a human population selected at random, and living in a Bolivian community, highly endemic for Chagas disease, was investigated combining together clinical, parasitological and molecular approaches, finding the anti-R13 reactivity was associated with early infection and not to cardiac pathology.
American histoplasmosis in developing countries with a special focus on patients with HIV: diagnosis, treatment, and prognosis
- P. Couppié, C. Aznar, B. Carme, Mathieu Nacher
- MedicineCurrent Opinion in Infectious Diseases
- 1 October 2006
Direct examination of May–Grünwald–Giemsa-stained smears or tissues in suspected histoplasmosis is a simple means of confirming the diagnosis in resource-poor settings and further refine indication criteria to guide first-line treatment choice between amphotericin B and itraconazole.
Fatal outbreak of human toxoplasmosis along the Maroni River: epidemiological, clinical, and parasitological aspects.
- M. Demar, D. Ajzenberg, B. Carme
- Medicine, BiologyClinical Infectious Diseases
- 1 October 2007
Molecular analysis demonstrated that identical isolates of only 1 atypical strain were responsible for at least 5 of the 11 cases of toxoplasmosis in the outbreak in Patam, a Surinamese village near the French Guianan border.
Histoplasmosis in HIV-Infected Patients: A Review of New Developments and Remaining Gaps
- A. Adenis, C. Aznar, P. Couppié
- Medicine, BiologyCurrent Tropical Medicine Reports
- 28 March 2014
Progress has been made in DNA patterns of strains and understanding of pathogenesis, and hopefully these will help identify new therapeutic targets and new diagnostic tools and therapeutics developments have still not been made available in most endemic regions.
Ecologic Correlates of Toxoplasma gondii Exposure in Free-ranging Neotropical Mammals
- Benoit de Thois, M. Demar, C. Aznar, B. Carme
- BiologyJournal of Wildlife Diseases
- 1 April 2003
A serologic survey for Toxoplasma gondii in 18 free-ranging forest mammal species in French Guiana was undertaken with a direct agglutination test and terrestrial mammals were significantly more exposed to T. Gondii than other mammals.
Analytical Validation of Quantitative Real-Time PCR Methods for Quantification of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients.
- J. Ramírez, C. Cura, A. Schijman
- Medicine, BiologyJournal of Molecular Diagnostics
- 1 September 2015
Histoplasmosis and acquired immunodeficiency syndrome: a study of prognostic factors.
- P. Couppié, M. Sobesky, B. Carme
- MedicineClinical Infectious Diseases
- 2004
It is found that dyspnea, a platelet count of <100,000 platelets/mm3, and lactate dehydrogenase levels of >2 times the upper limit of the normal range were significantly independently associated with the death of the patient during the first 30 days of antifungal treatment.
...
...