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In Vivo Models Used for Evaluation of Potential Antigastroduodenal Ulcer Agents
Peptic ulcer is among the most serious gastrointestinal diseases in the world. Several orthodox drugs are employed for the treatment of the disease. Although these drugs are effective, they produceExpand
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The popular herbal antimalarial, extract of Cryptolepis sanguinolenta, is potently cytotoxic.
  • C. Ansah, N. Gooderham
  • Biology, Medicine
  • Toxicological sciences : an official journal of…
  • 1 December 2002
The aqueous root extract of Cryptolepis sanguinolenta (CSE) is a popular antimalarial in West African ethnomedicine. Cryptolepine (CLP), the major alkaloid of the plant, is a cytotoxic DNAExpand
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A review of the anticancer potential of the antimalarial herbal cryptolepis sanguinolenta and its major alkaloid cryptolepine.
  • C. Ansah, K B Mensah
  • Medicine, Biology
  • Ghana medical journal
  • 1 September 2013
Cryptolepis sanguinolenta (Lindl.) Schltr (Periplocaceae), has a longstanding traditional use in the treatment of malaria in the West African region. Recent evidence suggests that the aqueous extractExpand
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Anti-inflammatory and antioxidant properties of the root extract of Carissa edulis (forsk.) Vahl (apocynaceae)
Root extracts of Carissa edulis (Forsk.) Vahl (Apocynaceae) are used for the treatment several pathological states including inflammatory disorders. The present study was undertaken to evaluate theExpand
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Synergistic anti-malarial action of cryptolepine and artemisinins
BackgroundCryptolepine (CPE) is the major indoloquinoline isolated from the popular West African anti-malarial plant, Cryptolepis sanguinolenta. CPE possesses various pharmacological activities withExpand
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Terminalia ivorensis A. Chev. Ethanolic Stem Bark Extract Protects Against Gentamicin-Induced Renal and Hepatic Damage in Rats
The aim of present study was to investigate the possible protective effects of an ethanolic stem bark extract of Terminalia ivorensis on gentamicin – induced nephrotoxicity and hepatotoxicity in maleExpand
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Antibiotic use during pregnancy: a retrospective study of prescription patterns and birth outcomes at an antenatal clinic in rural Ghana
BackgroundBabies are increasingly being exposed to antibiotics intrapartum in the bid to reduce neonatal and maternal deaths. Intrapartum antibiotic exposure, including even those considered safe inExpand
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In Vivo Assessment Of The Toxic Potential Of Dissotis Rotundifolia Whole Plant Extract In Sprague–Dawley Rats
Abstract Objective To assess the toxic potential of Dissotis rotundifolia ( D. rotundifolia ) whole plant extract in Spraque–Dawley rats within a 2-week period of administration. Methods MethanolicExpand
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