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Early events in Epstein-Barr virus infection of human B lymphocytes.
The sequence of Epstein-Barr virus (EBV) and B lymphocyte changes in the 3 days following acute infection was analyzed. By 16 hr the average infected lymphocyte had 1 EBV episome. Nuclear protein-2… Expand
Activation of Transcription Factors NF-κB and NF-IL-6 by Human Immunodeficiency Virus Type 1 Protein R (Vpr) Induces Interleukin-8 Expression
- Philippe P Roux, C. Alfieri, M. Hrimech, É. Cohen, J. Tanner
- Medicine, Biology
- Journal of Virology
- 15 May 2000
ABSTRACT Human immunodeficiency virus (HIV)-positive individuals express elevated levels of interleukin-8 (IL-8), which is believed to be responsible for some of the clinical manifestations occurring… Expand
Induction of interleukin-6 after stimulation of human B-cell CD21 by Epstein-Barr virus glycoproteins gp350 and gp220.
The cellular receptor for Epstein-Barr virus (EBV) is the type 2 complement receptor, CD21. At initial infection, EBV virion glycoproteins gp350 and gp220 bind to CD21. We report here that the… Expand
Epstein-Barr virus infection in transplant recipients: Summary of a workshop on surveillance, prevention and treatment.
- U. Allen, C. Alfieri, +10 authors K. Jacobson
- The Canadian journal of infectious diseases…
Diseases caused by the Epstein-Barr virus are of great significance among organ transplant recipients. One of these diseases, post-transplant lymphoproliferative disease, is a major complication… Expand
Erratum: Early events in Epstein-Barr virus infection of human B lymphocytes (Virology (1991) 181 (595-608))
Induction of germ-line and mature C epsilon transcripts in human B cells stimulated with rIL-4 and EBV.
- H. Jabara, L. Schneider, +5 authors D. Vercelli
- Biology, Medicine
- Journal of immunology
- 15 November 1990
EBV and rIL-4 induce T cell-independent IgE production by normal human B cells. We demonstrate here that EBV and IL-4 induced the synthesis of IgE by surface IgE-negative B cell precursors isolated… Expand
Inhibition of IκB kinase by thalidomide increases hepatitis C virus RNA replication
Summary. Hepatic fibrosis is an integral element in the progression of chronic liver disease. Elevated hepatic interleukin (IL)‐8 is an important contributor to fibrosis in patients chronically… Expand
Effect of mycophenolic acid on Epstein-Barr virus infection of human B lymphocytes.
- C. Alfieri, A. Allison, E. Kieff
- Medicine, Biology
- Antimicrobial Agents and Chemotherapy
- 1 January 1994
The effect of mycophenolic acid (MPA) on the growth of Epstein-Barr virus (EBV)-transformed B cells and on EBV lytic-cycle gene expression was investigated. MPA inhibited the proliferation of newly… Expand
Antibody and antibody-dependent cellular cytotoxicity responses against the BamHI A rightward open-reading frame-1 protein of Epstein-Barr virus (EBV) in EBV-associated disorders.
Antibody-dependent cellular cytotoxicity (ADCC) is an important antiviral effector mechanism. ADCC to the protein encoded by the Epstein-Barr virus (EBV) BamHI A rightward open-reading frame-1… Expand
Epstein-Barr virus (EBV) early-antigen serologic testing in conjunction with peripheral blood EBV DNA load as a marker for risk of posttransplantation lymphoproliferative disease.
- L. Carpentier, B. Tapiéro, F. Alvarez, Carole Viau, C. Alfieri
- The Journal of infectious diseases
- 15 December 2003
Epstein-Barr virus (EBV) early-antigen (EA) serologic profile was examined in conjunction with peripheral blood EBV DNA load, to assess its value in evaluating the risk of developing… Expand