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Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia.
OBJECTIVE The purpose of this study was to assess if simvastatin has an anti-inflammatory activity in patients with hypercholesterolemia. BACKGROUND Simvastatin, an inhibitor ofExpand
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Non‐alcoholic fatty liver syndrome: A hepatic consequence of common metabolic diseases
Background and Aims: The association of liver steatosis with a number of common metabolic conditions has been suggested. The aim of the present study was to evaluate the clinical features of subjectsExpand
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Serum Metalloproteinase 9 Levels in Patients with Coronary Artery Disease: A Novel Marker of Inflammation
Background The finding that expression of metalloproteinases (MMPs) is induced in atherosclerotic plaques prone to rupture suggests the possibility that patients with atherosclerotic diseases wouldExpand
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Association between low-grade disseminated intravascular coagulation and endotoxemia in patients with liver cirrhosis.
BACKGROUND & AIMS Hyperfibrinolysis may complicate the clinical course of liver cirrhosis. The aim of this study was to evaluate if, in cirrhosis, hyperfibrinolysis is primary or secondary toExpand
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Simvastatin reduces monocyte-tissue-factor expression type IIa hypercholesterolaemia
Inhibitors of 3-hydroxy-methyl-glutaryl coenzyme A reductase have been shown to reduce cardiovascular events in patients with raised and average serum cholesterol. It is unclear whether this effectExpand
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Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group.
Thrombotic complications of pulmonary circulation occur in patients with chronic obstructive pulmonary disease (COPD). In the present study, we sought to evaluate in vivo platelet activation throughExpand
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Preparation and biodistribution of 99m technetium labelled oxidized LDL in man.
Radiolabelled autologous low density lipoprotein (LDL) has previously been used to study in vivo distribution and metabolism of native-LDL. Non-invasive imaging of atherosclerotic lesions usingExpand
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Soluble P-selectin as a marker of platelet hyperactivity in patients with chronic obstructive pulmonary disease.
A comparative analysis between soluble (s) P-selectin and von Willebrand Factor (vWF) was performed in 40 patients with chronic obstructive pulmonary disease (COPD) and 20 healthy subjects, with theExpand
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Inhibition of tissue-factor-mediated thrombin generation by simvastatin.
A previous study has shown that simvastatin reduces in vivo clotting activation and monocyte tissue factor (TF) expression. This effect, however, was only in part attributable to the reduction ofExpand
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Recurrent Carotid Disease: Will Stents Be an Alternative to Surgery?
Purpose: To report the results of balloon angioplasty in recurrent carotid occlusive disease and evaluate the potential for stent implantation. Methods and Results: Between April 1991 and SeptemberExpand
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