Share This Author
Inhibition of allergic reactions by cromoglycate and by a new antiallergy drug U-42,585E. II. Activity in primates against aerosolized Ascaris suum antigen.
Two parameters used to measure lung function, respiratory rate increase and tidal volume decrease, were significantly altered in a dose-related fashion by U-42,585E when the latter was administered either by the intravenous, intrabronchial, or the oral route. Expand
Inhibition of allergic reactions by cromoglycate and by a new anti-allergy drug U-42,585E. I. Activity in rats.
- H. Johnson, C. A. VanHout, J. B. Wright
- Chemistry, Medicine
- International archives of allergy and applied…
A new inhibitor of IgE-mediated allergic reactions has been studied in rats and its ability to inhibit ionophore-induced 45Ca++ flux correlates well with inhibition of histamine release. Expand
The Enhanced Efficacy of Disodium Cromoglycate (DSCG) in DSCG Predosed Rats
Summary The predosing of rats with different doses of DSCG followed by a sufficient time interval so that the drug's effect was gone, then injection of another DSCG dose with antigen led to a high… Expand