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Pretranslational suppression of cytochrome P-450h (IIC11) gene expression in rat liver after administration of interferon inducers.
  • E. Morgan, C. A. Norman
  • Biology, Medicine
  • Drug metabolism and disposition: the biological…
  • 1 September 1990
TLDR
Results indicate that suppression of rat liver P- 450 isozymes by interferon inducers is not confined to P-450h, and that the primary mechanism(s) is at a pretranslational level. Expand
Is carbon monoxide a workplace teratogen? A review and evaluation of the literature.
TLDR
Fetal outcome was related to two major indices of carbon monoxide exposure: maternal blood carboxyhaemoglobin levels and maternal toxicity. Expand
Formation and persistence of DNA adducts in rats following intraperitoneal administration of 1,8-dinitropyrene.
TLDR
The loss of DNA adducts was biphasic, with an initial rapid decrease followed by a slower rate of adduct removal, and over a 2 week period the relative adduct labelling values declined in all tissues. Expand
DNA adduct formation in primary rabbit tracheal epithelial cells following treatment with 1,8-dinitropyrene and its partially reduced derivative, 1-nitro-8-nitrosopyrene.
TLDR
Relative adduct labelling values were consistently an order of magnitude higher with 1,8-NONO2 than with 1-8-DNP, suggesting that reduction of a nitro group of 1,9-dinitropyrene to aNitroso group may be a rate-limiting step in the cells. Expand
A Comparison of Public Support for Moderate and Extreme Terrorism
The purpose of this paper is to 'Compare Public Support for Moderate Terrorism and Extreme Terrorism' in high terror active nations (India, Iraq, Nigeria); medium terror active nations (China,Expand