C de Lezenne Coulander

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The low death rate from coronary heart disease among the Greenland Eskimos has been ascribed to their high fish consumption. We therefore decided to investigate the relation between fish consumption and coronary heart disease in a group of men in the town of Zutphen, the Netherlands. Information about the fish consumption of 852 middle-aged men without(More)
The Zutphen Study is a longitudinal investigation among middle-aged men of relationships between diet, other risk characteristics, and coronary heart disease (CHD). In 1960, dietary data were collected by the cross-check dietary history method. CHD mortality data were collected during 10 years of follow-up. The 14 men with CHD at baseline consumed 524(More)
Information about trace metals and coronary heart disease risk indicators was collected in 1977 among 152 men aged 57-76 years in the town of Zutphen, the Netherlands. Serum zinc, serum copper, blood cadmium, and blood lead were determined by atomic absorption spectrometry and serum lithium by flame emission spectrometry. After uni- and multivariate(More)
In 1960, 871 middle-aged men in the town of Zutphen, The Netherlands, participated in a survey of risk indicators (including diet) for coronary heart disease (CHD). Information was collected about the usual food intake for the 6--12 months before the interview by the cross-check dietary history method. During 10 years of follow-up, 107 men died from all(More)
To clarify whether the inverse relation between habitual fish consumption and cardiovascular mortality in the Dutch town of Zutphen could be explained by changes in platelet function or fibrinolysis, 40 healthy elderly men were selected from the Zutphen study population on the basis of their fish consumption over the last 26 years. In the high-fish group (n(More)
Within the Zutphen Study dietary surveys using the cross-check dietary history method were carried out in 1960, 1965, 1970, and 1985. Of the 872 men aged 40-59 y examined in 1960, 315 participated in all four surveys. In 1985 a small random sample of 51 men aged 40-59 y was also investigated. Between 1960 and 1985 the consumption of bread, potatoes, and(More)
In the Zutphen Study, cholesterol determinations were carried out in 1960 in serum of 829 middle-aged men. Between 1960 and 1985, detailed information was collected on morbidity and mortality in these men. During 25 years of follow-up, 179 men developed myocardial infarctions and 203 developed cancer. During this period, 110 men died of myocardial(More)
Repeated risk factor measurements reduce the amount of random error due to intraindividual variation. Annual measurements of serum cholesterol and systolic blood pressure were done in a cohort of 878 men, aged 40-59 years, between 1960 and 1970. This study examined for both risk factors the association with the incidence of myocardial infarction (MI) during(More)
In a non-concurrent cohort study, the data from medical examinations of 78,612 Dutch men at the age of 18 were linked to mortality registrations over a follow-up period of 32 years. Body weight and height, blood pressure, resting pulse rate, education, birth order and a health score were recorded. The average Body Mass Index was 20.8 kg/m2. About 5% of the(More)
The Dutch part of Kempenland has been exposed to cadmium pollution since the last century. Experimental data suggest effects by cadmium on reproduction such as diminished fertility, decreased foetal growth, and specific malformations. Use was made of a historical cohort of dairy cows, ascertained from a surveillance program conducted by the regional(More)