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Long noncoding RNAs (lncRNAs) have been shown to regulate tumor biology and might be used for cancer diagnosis, prognosis and potential therapeutic targets. Although up-regulation of lncRNA UCA1 (urothelial carcinoma-associated 1) in several cancers has been found, its role in gastric cancer remains elusive. The aim of this study was to detect the(More)
The development of high performance, low computational complexity detection algorithms is a key challenge for real-time multiple-input multiple-output (MIMO) communication system design. The fixed-complexity sphere decoder (FSD) algorithm is one of the most promising approaches, enabling quasi-ML decoding accuracy and high performance implementation due to(More)
A new method for microvascular anastomosis was developed and compared with conventional techniques, using the rabbit femoral artery. A dissolvable stent biomaterial was placed in the lumen to expose the vessel walls clearly, so that the quality of anastomosis could be improved. The results showed no significant difference in immediate and late patency rates(More)
The amino acid sequences of both human class 1 and 2 aldehyde dehydrogenase (ALDH) and the sequences of the genes coding for them are known. Based on this sequence data, we designed primers and isolated the full-length cDNAs encoding both isozymes from a human liver mRNA pool. cDNAs were subcloned in the plasmid pT7-7 and expressed in Escherichia coli with(More)
In this article, we study the problem of testing the mean vectors of high dimensional data in both one-sample and two-sample cases. The proposed testing procedures employ maximum-type statistics and the parametric bootstrap techniques to compute the critical values. Different from the existing tests that heavily rely on the structural conditions on the(More)
Mutational analysis allowed us to rule out an essential role for the histidine residues and for serine 74 in mammalian aldehyde dehydrogenase. The later though, was found to be important in coenzyme interaction. The function of the serine could not be replaced by threonine or by cysteine. The absolute requirement for cysteine 302 and for glutamate 268 was(More)
One histidine residue (H235) is conserved in all known aldehyde dehydrogenases (ALDH), from Escherichia coli to human, except for those from P. oleovorans and rat hepatoma. Kinetic studies with horse liver mitochondrial ALDH indicated that a group with a pKa of 7 may be involved in the active site. Using site-directed mutagenesis, the four conserved(More)
An approach to distributed plant-wide analysis and control of networked systems with varying time delay in discrete time is presented, with a particular focus on chemical process systems. Plant-wide stability and performance conditions are ensured by putting constraints on the dissipativity properties of the plant-wide system, which is a linear function of(More)