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The motor representation of the body musculature was studied in 11 adult mice by using ICMS. The motor responses elicited from both granular and agranular cortical fields showed that the mouse motor cortex is topographically organized; however, within the representation of individual body-parts the movements are multiply represented. In addition, several(More)
We studied the organization of the forepaw barrel subfield (FBS) in layer IV of adult rat somatosensory cortex using the mitochondrial marker cytochrome oxidase and related this organization to the representation of the forepaw. The FBS is an ovoid structure consisting of barrels and barrel-like structures, the most conspicuous of which form four centrally(More)
Neurons in layer IV of rat somatosensory (SI) barrel cortex receive punctate somatic input from well-defined regions of the periphery. Following peripheral deafferentation, SI neurons in deafferented cortex respond to new input from neighboring regions of the skin surface. The precise mechanism(s) through which this occurs is unknown, although(More)
Our objective was to test the hypothesis that suppression of GABAergic inhibition results in an enhancement of responses to stimulation of the surround receptive field. Neurons in the forepaw barrel subfield (FBS) in rat first somatosensory cortex (SI) receive short latency suprathreshold input from a principal location on the forepaw and longer latency(More)
Maternal alcohol exposure results in a variety of neurodevelopmental abnormalities that include cognitive and sensorimotor dysfunctions that often persist into adulthood. Many reports of central nervous system disturbances associated within a clinical diagnosis of fetal alcohol syndrome point toward disturbances in central information processing. In this(More)
The physiological representation of the shoulder and surrounding body was examined in layer IV of somatosensory cortex (SI) in rats that had underground removal of the forelimb, either as newborns on postnatal day three (PND-3) or as adults (at least 8 weeks of age). Electrophysiological recordings were used to map the shoulder and body representations(More)
We previously reported that 6-16 weeks after forelimb amputation in adult rats, neurons in layer IV of rat first somatosensory cortex (SI) in the forepaw barrel subfield (FBS) associated with the representation of the forepaw became responsive to new input from the shoulder (Pearson et al. 1999). These new shoulder-responsive sites in deafferented FBS had(More)
We examined the physiological properties and morphology of neurons in the forepaw barrel subfield (FBS) in somatosensory cortex (SI) of adult rats using in vivo intracellular recording and biocytin labeling techniques. Our results show that both pyramidal and non-pyramidal type spiny neurons can be activated with short latency by peripheral stimulation. FBS(More)
In-utero alcohol exposure produces sensorimotor developmental abnormalities that often persist into adulthood. The rodent cortical barrel field associated with the representation of the body surface was used as our model system to examine the effect of prenatal alcohol exposure (PAE) on early somatosensory cortical development. In this study, pregnant(More)
Two families of solutions of a generalized non-Abelian Toda lattice are considered. These solutions are expressed in terms of quasideterminants, constructed by means of Darboux and binary Darboux transformations. As an example of the application of these solutions, we consider the 2-periodic reduction to a matrix sine-Gordon equation. In particular, we(More)