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- Le Bayon, J. A. Otero, P. M. Suárez, C. Tasis
- Mathematical biosciences
- 2016

Optimal control theory is one of the most important tools in the development of new therapeutic protocols for treating infections. In this work, we present an algorithm able to deal with high-dimensional problems with bounded controls. The optimal solution is obtained by minimizing a positive-definite treatment cost function. Our method, based on… (More)

- L. Bayón, J. A. Otero, M. M. Ruiz, P. M. Suárez, C. Tasis
- J. Computational Applied Mathematics
- 2012

- L. Bayón, Pedro Fortuny Ayuso, J. A. Otero, P. M. Suárez, C. Tasis
- J. Computational Applied Mathematics
- 2016

with zi ∈ { Ĉ[0, T ] |zi(0) = 0, zi(T ) = bi } , with technical constraints for the consumption rate over time: mi ≤ żi(t) ≤Mi, ∀i = 1, . . . , n. We abstract from this situation to tackle a general problem which studies a production process whose efficiency of production with respect to each input depends on time, on the stock of the various inputs, and on… (More)

- L. Bayón, P. J. García Nieto, R. García-Rubio, J. A. Otero, P. M. Suárez, C. Tasis
- J. Computational Applied Mathematics
- 2017

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