C. Santhosh

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We report here results of a single-cell Raman spectroscopy study of stress effects induced by silver nanoparticles in human mesenchymal stem cells (hMSCs). A high-sensitivity, high-resolution Raman Tweezers set-up has been used to monitor nanoparticle-induced biochemical changes in optically-trapped single cells. Our micro-Raman spectroscopic study reveals(More)
In this paper, a system for oral cancer screening using Laser Induced Fluorescence(LIF) has been developed. A hybrid approach of classification using Support Vector Machine (SVM) and Random Forest (RF) classifier's is proposed. Performance of the classifier is evaluated using several features types such as Wavelet, DFT, LDFT, ILDFT, DCT, LDCT and Slopes(More)
In the present work we discuss the potential of recently developed classification algorithm, Learning Vector Quantization (LVQ), for the analysis of Laser Induced Fluorescence (LIF) Spectra, recorded from normal and malignant bladder tissue samples. The algorithm is prototype based and inherently regularizing, which is desirable, for the LIF spectra because(More)
The role of neuro-inflammation in diverse, acute and chronic brain pathologies is being increasingly recognized. Neuro-inflammation is accompanied by increased levels of both pro-and anti-inflammatory cytokines; these have deleterious as well as protective/reparative effects. Inflammation has varying effects on neurogenesis and is a subject of intense(More)
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