C. S. Woodhouse

Learn More
Safety of administration of a vindesine (VDS)-anti-CEA conjugate and its ability to localise after radiolabelling were investigated in patients with advanced metastatic carcinoma (4 colorectal and 4 ovarian). For imaging, patients received between 230 and 520 micrograms of 131I labelled antibody. In 5, localisation of conjugate was demonstrated, in another(More)
The expression of carcinoembryonic antigen (CEA) in gastric malignancies has been assessed using a monoclonal antibody in an immunoperoxidase technique. Of 119 primary tumours examined, 92% reacted with the antibody. Metastases were available for 81 of the patients and 83% were CEA positive. A noteworthy observation was the detection of malignant cells in(More)
EIGHTY TO NINETY PER CENT of patients with lung cancer are potential candidates for chemotherapy (Selawry, 1977). At present a major limitation to the use of chemotherapeutic agents is their lack of specific anti-tumour activity. Doses required for adequate cancer treatment are invariably accompanied by unwanted systemic side effects, myelosuppression,(More)
  • 1