C. S. Chen

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A relatively stereotyped seizure reaction can be triggered by the ‘offset’ of an intense bell sound in C57BL/6J mice. Susceptibility to this offset-induced audiogenic seizure was found to depend upon the age of the animals tested (higher in older mice) and the duration of the noise exposure (more effective with longer exposure).
Audiogenic seizure risk can be induced in genetically seizure resistant mice by exposure to an intense noise a few days prior to testing for seizure. This experiment demonstrates that the priming induced seizure risk can develop within 6–16 h after priming. It was argued that this finding suggested an alternative hypothesis of priming involving peripheral(More)
Une crise audiogène peut être provoquée chez les souris BALB/c génétiquement non influencées agées de 21 jours, en les exposant à un bruit fort (sensibilisation). Cependant, cet effect de sensibilisation pourrait être considérablement réduit si les souris préalablement anesthésiées à l'éther, sont d'abord exposées au même bruit à l'âge de 14 jours.
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