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The vitamin D receptor (VDR) has been detected in breast tumor cells. We tested the hypothesis that VDR gene polymorphism might influence the outcome of women affected by breast cancer. A total of 88 breast cancer patients were recruited: 50 women were affected by newly diagnosed breast cancer whereas 38 women suffered from relapsing disease. The individual(More)
The brain weight of 100 fresh cadavers of Italian subjects (60 males and 40 females), aged between 17 and 84 years, was obtained and the corrected circumference of the following blood vessels was measured: basilar artery, internal carotid arteries, anterior and posterior cerebral arteries, and anterior and posterior communicating arteries. The cerebral(More)
We describe the effect of a 0.2 tesla (T) static magnetic field generated by a magnetic resonance tomograph and of vitamin D treatment on a human breast cancer cell line (MCF-7). Cell damage and proliferation were monitored by measuring the incorporation of [3H]thymidine in duplicating DNA and by the clonogenic assay. [3H]Thymidine incorporation in MCF-7(More)
A new method for the detection of fecal occult blood was tested in a clinical setting. The test is performed by placing a chemically treated paper pad in the toilet bowl after a bowel movement and observing for color change on the pad. This method eliminates the mechanical task of handling or gathering stool by the patient. Forty-four valid trials were(More)
Ninety-four out of 114 physicians who took part in a continuing medical education course on flexible sigmoidoscopy were contacted 12 to 18 months later. Ninety per cent (85) were now using flexible sigmoidoscopy in their office practice. Complete demographic and procedure-outcome information (number of procedures performed, average depth of insertion, time(More)
The corrected circumference of the pulmonary trunk, its branches and ascending aorta as well as the maximum diameter of the principal bronchi, were measured in 120 human fresh cadavers of subjects (60 males and 60 females) aged between 27 and 91 years, died of natural causes. The statistical analysis of the obtained data yielded the following main results:(More)
In light of the recent advances regarding the role of vascularity in Alzheimer’s disease (AD) pathophysiology, the relationship between plasma levels and activities of the major antioxidant molecules and the carotid intima–media thickness (C-IMT) of older persons with no or very mild cognitive impairment was evaluated. The underlying hypothesis is that the(More)
This study investigates the relationship between cognitive dysfunction or delirium detected in the early post-surgical phase and the 1-year mortality among 514 hip fracture hospitalized older persons. Patients with early cognitive dysfunction or delirium experienced a 2-fold increased mortality risk. Early post-operative cognitive dysfunction and delirium(More)
Parallel computing seems to be the solution for molecular dynamics of large atomic systems, such as proteins in water environments, but the simulation time critically depends on the processor allocation strategy. A study of the optimal processor allocation based on a space decomposition algorithm for single instruction multiple data flow mesh computers is(More)