Learn More
Angiotensin II (Ang II) is a risk factor for cardiovascular disease. We used a traditional Chinese medicine, alpinate oxyphyllae fructus (AOF), to evaluate its effect on Ang II-induced cardiac apoptosis and mitochondrial dysfunction. Ang II-treated H9c2 cells were administered AOF of 20-100 µg/mL concentrations. Ang II significantly increased TUNEL-positive(More)
  • C R Wang
  • Journal of microbiology, immunology, and…
  • 2000
The CD4 loosing (CD4L) mice have a novel defect in CD4 expression where CD4 mRNA is alternatively spliced to delete a transmembrane portion to give rise to the secretion of soluble CD4 (sCD4) without the expression of membrane-bound CD4. To analyze the role of sCD4 in immune responses in CD4L mice, experiments have been done by comparing CD4L mice with CD4(More)
  • C R Wang
  • Journal of microbiology, immunology, and…
  • 2001
To analyze the role of soluble CD4 (sCD4) in antibody (Ab) responses in CD4 loosing (CD4L) mice, experiments have been done in comparing CD4L mice with CD4 knockout (CD4KO) mice on the same C57BL/6 background. The CD4L mice have a defect in CD4 expression where CD4 mRNA is alternatively spliced so that a transmembrane portion is deleted and sCD4 are(More)
  • 1