C. R. Müller

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Introduction In addition to thètestis determining factor' (SRY), the Y chromosome harbours genes important for spermatogenesis. Thèazoospermia factor' (AZF) on the long arm of the Y chromosome, originally de®ned by Tiepolo & Zuffardi (1976), is now progressively being dissected into discrete genes (Lahn & Page, 1997; Vogt et al., 1997). The deletion of the(More)
Nuclear magnetic resonance spectroscopy and magnetic resonance imaging at the ultimate sensitivity limit of single molecules or single nuclear spins requires fundamentally new detection strategies. The strong coupling regime, when interaction between sensor and sample spins dominates all other interactions, is one such strategy. In this regime, classically(More)
  • W. Bochtler, L. Gragert, Z. I. Patel, J. Robinson, D. Steiner, J. A. Hofmann +9 others
  • 2016
The accuracy of human leukocyte antigen (HLA)-matching algorithms is a prerequisite for the correct and efficient identification of optimal unrelated donors for patients requiring hematopoietic stem cell transplantation. The goal of this World Marrow Donor Association study was to validate established matching algorithms from different international donor(More)
The degree of HLA concordance with the patient has long been known to be the major donor-related prediction factor for the success of hematopoietic stem cell transplantations and, with the progress of HLA typing technology, selection criteria became more stringent with regard to the recommended loci and resolution. A late refinement was HLA-C matching,(More)
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