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The precision of the Ballard scale for assessing gestational age (GA) was evaluated in a consecutive sample of 227 preterm and/or low-birth-weight neonates. Each newborn was rated independently by two neonatologists and the difference in GA estimation between them was computed. The estimated precision was not high, the 95% tolerance interval estimate being(More)
Empty sella is a descriptive term used to define an anatomoradiological entity characterized by penetration of cerebrospinal fluid (CSF) and subarachnoid space within the sella cavity. To clarify the relationship between empty sella and the endocrinological abnormalities frequently associated in pediatric patients, we examined the hormonal and radiological(More)
To search for the presence of morphostructural abnormalities of the hypothalamus - pituitary region in GHD children MRI was performed in 28 IGHD pts (21M, 7F, age 10.1±3.4, range 4.2-18) and in 15 healthy age matched controls (10M, 5F, age 8.3±2.9, range 4 to 12.4). Isolated GHD had been demonstrated in 19/28 pts, multiple pituitary hormones deficiency(More)
We evaluated the tolerance and effectiveness of the oral clonidine test for GH in 75 children, 84% with hyposomia and 16% with other diseases. The test was well tolerated, since 97% of the examined children had no side effects with the exception of occasional drowsiness, pallor and myosis of short duration. Two of the children at the end of the test, had(More)
In the last few years the therapeutic management of GHD children has been improved by the recent synthesis of GH by DNA recombinant technique (rGH). rGH made it possible to overcome the problems of availability and purity of extractive GH, obtaining the same results (in growth velocity) without any information as regards late side effects of such a(More)
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