Learn More
The relationship between the in vivo irritation potential of sodium lauryl sulfate (SLS) and linear alkyl benzene sulfonate (LAS) and the ability of these two surfactants to remove lipid from the stratum corneum (SC) in vitro were investigated. Either surfactant removes detectable levels of lipids only above its critical micelle concentration (CMC). At high(More)
The urea-induced unfolding reaction of the alpha subunit of tryptophan synthase was monitored by examining the chemical shifts and peak areas of the C epsilon protons of the four histidine residues with 1D NMR spectroscopy. In a native base-line region defined by tyrosine absorbance and far-UV circular dichroism spectroscopy, histidine-146 appears to(More)
The formation of stable transition metal complexes between pentaammineruthenium(III) and the imidazole moiety of histidine residues in ribonuclease A is described. Studies of the kinetics of incorporation suggest that three of the four histidines are reactive and ion-exchange chromatography affords the isolation of three derivatives containing a single(More)
  • 1